Zinc in PDB 8fwo: Crystal Structure of Sars-Cov-2 Papain-Like Protease

All present enzymatic activity of Crystal Structure of Sars-Cov-2 Papain-Like Protease:
3.4.19.12;

The structure of Crystal Structure of Sars-Cov-2 Papain-Like Protease, PDB code: 8fwo was solved by E.H.S.Bezerra, A.S.Soprano, C.C.C.Tonoli, P.F.V.Prado, J.C.Da Silva, K.G.Franchini, D.B.B.Trivella, C.E.Benedetti, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.65 / 1.80
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	83.005, 83.005, 133.964, 90, 90, 120
R / Rfree (%)	18.1 / 21.7

The structure of Crystal Structure of Sars-Cov-2 Papain-Like Protease also contains other interesting chemical elements:

Chlorine

(Cl)

3 atoms

The binding sites of Zinc atom in the Crystal Structure of Sars-Cov-2 Papain-Like Protease (pdb code 8fwo). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Sars-Cov-2 Papain-Like Protease, PDB code: 8fwo:

Zinc binding site 1 out of 1 in the Crystal Structure of Sars-Cov-2 Papain-Like Protease


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Sars-Cov-2 Papain-Like Protease within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn404 b:71.9 occ:0.00 SG A:CYS189 2.2 47.8 1.0 SG A:CYS224 2.2 69.1 1.0 SG A:CYS226 2.2 65.3 1.0 SG A:CYS192 2.2 82.3 1.0 CB A:CYS224 2.8 51.4 1.0 CB A:CYS189 3.1 70.8 1.0 CB A:CYS192 3.3 84.2 1.0 CB A:CYS226 3.3 80.0 1.0 N A:CYS226 4.0 82.4 1.0 N A:CYS192 4.2 80.2 1.0 CA A:CYS224 4.2 71.5 1.0 CA A:CYS226 4.2 86.7 1.0 CA A:CYS192 4.4 79.9 1.0 CA A:CYS189 4.5 72.3 1.0 C A:CYS224 4.5 78.4 1.0 CB A:LYS228 4.6 64.4 1.0 N A:THR225 4.7 84.4 1.0 CB A:THR191 4.7 64.4 1.0 N A:LYS228 4.7 57.7 1.0 C A:CYS226 4.9 84.4 1.0 O A:LYS228 4.9 64.9 1.0

E.H.S.Bezerra, A.S.Soprano, C.C.C.Tonoli, P.F.V.Prado, J.C.Da Silva, K.G.Franchini, D.B.B.Trivella, C.E.Benedetti. Crystal Structure of Sars-Cov-2 Papain-Like Protease To Be Published.