Zinc in PDB 9ir4: Cryo-Em Structure of Nipah Virus L-P (H1165Y) Polymerase Complex

All present enzymatic activity of Cryo-Em Structure of Nipah Virus L-P (H1165Y) Polymerase Complex:
2.1.1.375; 2.7.7.48; 2.7.7.88;

The binding sites of Zinc atom in the Cryo-Em Structure of Nipah Virus L-P (H1165Y) Polymerase Complex (pdb code 9ir4). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cryo-Em Structure of Nipah Virus L-P (H1165Y) Polymerase Complex, PDB code: 9ir4:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Cryo-Em Structure of Nipah Virus L-P (H1165Y) Polymerase Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of Nipah Virus L-P (H1165Y) Polymerase Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn2301 b:60.1 occ:1.00 ND1 A:HIS1421 2.1 53.0 1.0 NE2 A:HIS1423 2.1 55.9 1.0 SG A:CYS1239 2.3 64.2 1.0 SG A:CYS1236 2.3 66.0 1.0 CE1 A:HIS1423 2.7 55.9 1.0 CB A:CYS1236 2.8 66.0 1.0 CG A:HIS1421 3.0 53.0 1.0 CE1 A:HIS1421 3.1 53.0 1.0 CD2 A:HIS1423 3.3 55.9 1.0 CB A:HIS1421 3.3 53.0 1.0 CB A:CYS1239 3.7 64.2 1.0 ND1 A:HIS1423 3.9 55.9 1.0 N A:CYS1239 4.0 64.2 1.0 NE2 A:HIS1421 4.2 53.0 1.0 CD2 A:HIS1421 4.2 53.0 1.0 CG A:HIS1423 4.2 55.9 1.0 CA A:CYS1236 4.3 66.0 1.0 CA A:CYS1239 4.3 64.2 1.0 CB A:ILE1238 4.7 62.1 1.0 CG A:TYR1246 4.7 58.1 1.0 CD1 A:TYR1246 4.8 58.1 1.0 CA A:HIS1421 4.8 53.0 1.0 C A:ILE1238 4.9 62.1 1.0 C A:CYS1236 4.9 66.0 1.0 CD2 A:TYR1246 4.9 58.1 1.0 CG2 A:ILE1238 5.0 62.1 1.0 CE1 A:TYR1246 5.0 58.1 1.0

Zinc binding site 2 out of 2 in the Cryo-Em Structure of Nipah Virus L-P (H1165Y) Polymerase Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of Nipah Virus L-P (H1165Y) Polymerase Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn2302 b:87.7 occ:1.00 OE2 A:GLU1223 2.1 60.6 1.0 SG A:CYS1429 2.3 72.6 1.0 SG A:CYS1191 2.3 59.9 1.0 O A:CYS1428 3.0 76.9 1.0 CB A:CYS1191 3.1 59.9 1.0 CD A:GLU1223 3.2 60.6 1.0 CA A:CYS1191 3.4 59.9 1.0 SG A:CYS1428 3.6 76.9 1.0 C A:CYS1428 3.7 76.9 1.0 CG A:GLU1223 3.8 60.6 1.0 CB A:CYS1429 3.9 72.6 1.0 N A:SER1192 3.9 57.6 1.0 OE1 A:GLU1223 4.1 60.6 1.0 N A:CYS1429 4.2 72.6 1.0 CA A:CYS1429 4.2 72.6 1.0 C A:CYS1191 4.2 59.9 1.0 CA A:CYS1428 4.5 76.9 1.0 NZ A:LYS1024 4.6 48.3 1.0 N A:CYS1191 4.6 59.9 1.0 CB A:CYS1428 4.6 76.9 1.0 OG A:SER1192 4.9 57.6 1.0

Y.Shi, Q.Peng. Cryo-Em Structure of Nipah Virus L-P Polymerase Complex To Be Published.