Zinc in PDB 8cgv: Tiamulin Bound to the 50S Subunit

The structure of Tiamulin Bound to the 50S Subunit also contains other interesting chemical elements:

Magnesium	(Mg)	219 atoms
Potassium	(K)	83 atoms
Fluorine	(F)	2 atoms

The binding sites of Zinc atom in the Tiamulin Bound to the 50S Subunit (pdb code 8cgv). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Tiamulin Bound to the 50S Subunit, PDB code: 8cgv:

Zinc binding site 1 out of 1 in the Tiamulin Bound to the 50S Subunit


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Tiamulin Bound to the 50S Subunit within 5.0Å range: probe atom residue distance (Å) B Occ 3:Zn101 b:34.9 occ:1.00 ND1 3:HIS33 2.1 35.4 1.0 SG 3:CYS27 2.3 37.4 1.0 SG 3:CYS14 2.3 33.5 1.0 SG 3:CYS11 2.4 39.4 1.0 CE1 3:HIS33 3.1 36.4 1.0 CG 3:HIS33 3.1 33.5 1.0 CB 3:CYS27 3.4 38.4 1.0 CB 3:HIS33 3.4 32.9 1.0 CB 3:CYS11 3.5 41.5 1.0 N 3:CYS14 3.6 39.4 1.0 CB 3:CYS14 3.6 34.4 1.0 N 3:CYS11 3.7 40.7 1.0 CA 3:CYS14 3.8 37.3 1.0 CA 3:CYS11 4.0 44.2 1.0 NE2 3:HIS33 4.2 36.0 1.0 CD2 3:HIS33 4.2 35.8 1.0 C 3:ASN13 4.3 42.3 1.0 O 3:CYS11 4.3 45.6 1.0 C 3:CYS11 4.4 45.3 1.0 C 3:LEU10 4.5 41.5 1.0 CB 3:GLU30 4.6 48.7 1.0 CA 3:CYS27 4.6 39.7 1.0 CB 3:LEU10 4.7 40.8 1.0 N 3:ASN13 4.7 44.8 1.0 CB 3:ASN13 4.7 47.8 1.0 CA 3:ASN13 4.8 44.6 1.0 N 3:LEU10 4.8 36.4 1.0 CA 3:LEU10 4.9 39.6 1.0 CA 3:HIS33 4.9 30.3 1.0 O 3:ASN13 4.9 41.5 1.0 O 3:GLU30 5.0 39.5 1.0

H.Paternoga, C.Crowe-Mcauliffe, L.V.Bock, T.O.Koller, M.Morici, B.Beckert, A.G.Myasnikov, H.Grubmueller, J.Novacek, D.N.Wilson. Structural Conservation of Antibiotic Interaction with Ribosomes To Be Published.