Zinc in PDB 8bgu: Human MDM2-5S Rnp

All present enzymatic activity of Human MDM2-5S Rnp:
2.3.2.27;

The binding sites of Zinc atom in the Human MDM2-5S Rnp (pdb code 8bgu). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Human MDM2-5S Rnp, PDB code: 8bgu:

Zinc binding site 1 out of 1 in the Human MDM2-5S Rnp


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Human MDM2-5S Rnp within 5.0Å range: probe atom residue distance (Å) B Occ F:Zn501 b:242.0 occ:1.00 CB F:CYS308 2.5 239.7 1.0 CB F:CYS319 3.0 219.9 1.0 CB F:CYS305 3.1 247.8 1.0 N F:CYS308 3.1 239.7 1.0 CB F:CYS322 3.3 215.5 1.0 CA F:CYS308 3.3 239.7 1.0 N F:CYS322 3.9 215.5 1.0 C F:SER307 4.0 238.3 1.0 C F:CYS308 4.2 239.7 1.0 CA F:CYS322 4.2 215.5 1.0 CB F:SER307 4.3 238.3 1.0 CA F:CYS319 4.4 219.9 1.0 CA F:CYS305 4.4 247.8 1.0 CA F:SER307 4.5 238.3 1.0 N F:SER307 4.5 238.3 1.0 N F:ASN309 4.6 245.5 1.0 O F:SER307 4.9 238.3 1.0 N F:ARG321 4.9 208.8 1.0 CB F:ARG321 4.9 208.8 1.0 C F:ARG321 5.0 208.8 1.0 O F:CYS308 5.0 239.7 1.0 C F:CYS322 5.0 215.5 1.0

N.Castillo, M.Thoms, D.Flemming, H.M.Hammaren, R.Buschauer, M.Ameismeier, J.Bassler, M.Beck, R.Beckmann, E.Hurt. Structure of Nascent 5S Rnps at the Crossroad Between Ribosome Assembly and MDM2-P53 Pathways Nat.Struct.Mol.Biol. 2023.
ISSN: ESSN 1545-9985
DOI: 10.1038/S41594-023-01006-7