Zinc in PDB 8b3g: C(N)RL4CSA-Uvssa-E2-Ubiquitin Complex.

All present enzymatic activity of C(N)RL4CSA-Uvssa-E2-Ubiquitin Complex.:
2.3.2.27; 2.3.2.32;

The binding sites of Zinc atom in the C(N)RL4CSA-Uvssa-E2-Ubiquitin Complex. (pdb code 8b3g). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the C(N)RL4CSA-Uvssa-E2-Ubiquitin Complex., PDB code: 8b3g:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the C(N)RL4CSA-Uvssa-E2-Ubiquitin Complex.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of C(N)RL4CSA-Uvssa-E2-Ubiquitin Complex. within 5.0Å range: probe atom residue distance (Å) B Occ R:Zn201 b:605.9 occ:1.00 ND1 R:HIS80 2.0 542.5 1.0 SG R:CYS45 2.2 574.5 1.0 SG R:CYS42 2.3 520.5 1.0 SG R:CYS83 2.4 585.9 1.0 HB2 R:HIS80 2.5 542.5 1.0 CG R:HIS80 2.9 542.5 1.0 H R:HIS80 2.9 542.5 1.0 CE1 R:HIS80 3.1 542.5 1.0 CB R:HIS80 3.1 542.5 1.0 HB3 R:CYS45 3.1 574.5 1.0 HB2 R:CYS83 3.2 585.9 1.0 CB R:CYS45 3.3 574.5 1.0 HE1 R:HIS80 3.3 542.5 1.0 CB R:CYS83 3.4 585.9 1.0 H R:CYS45 3.4 574.5 1.0 CB R:CYS42 3.5 520.5 1.0 HB R:ILE44 3.6 563.0 1.0 HB2 R:CYS42 3.6 520.5 1.0 N R:HIS80 3.7 542.5 1.0 HB3 R:CYS42 3.7 520.5 1.0 HB3 R:CYS83 3.8 585.9 1.0 HB3 R:HIS80 3.9 542.5 1.0 CA R:HIS80 4.0 542.5 1.0 N R:CYS45 4.0 574.5 1.0 HB2 R:CYS45 4.0 574.5 1.0 CD2 R:HIS80 4.0 542.5 1.0 NE2 R:HIS80 4.1 542.5 1.0 HA R:CYS53 4.2 617.0 1.0 CA R:CYS45 4.3 574.5 1.0 H R:CYS83 4.4 585.9 1.0 CB R:ILE44 4.5 563.0 1.0 HA R:PHE79 4.5 507.8 1.0 HB2 R:CYS53 4.6 617.0 1.0 H R:ILE44 4.6 563.0 1.0 SG R:CYS53 4.7 617.0 1.0 O R:HIS80 4.7 542.5 1.0 HG12 R:ILE44 4.7 563.0 1.0 H R:ILE54 4.7 597.1 1.0 HB2 R:ASN47 4.7 565.8 1.0 CA R:CYS83 4.7 585.9 1.0 HA R:HIS80 4.7 542.5 1.0 H R:ASN47 4.8 565.8 1.0 C R:HIS80 4.8 542.5 1.0 HB3 R:PHE79 4.8 507.8 1.0 C R:PHE79 4.8 507.8 1.0 HD2 R:HIS80 4.8 542.5 1.0 N R:CYS83 4.9 585.9 1.0 H R:ARG46 4.9 536.4 1.0 HE2 R:HIS80 4.9 542.5 1.0 CA R:CYS42 4.9 520.5 1.0 HD1 R:PHE79 4.9 507.8 1.0 HG13 R:ILE44 4.9 563.0 1.0 CB R:CYS53 5.0 617.0 1.0 CG1 R:ILE44 5.0 563.0 1.0 C R:ILE44 5.0 563.0 1.0

Zinc binding site 2 out of 3 in the C(N)RL4CSA-Uvssa-E2-Ubiquitin Complex.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of C(N)RL4CSA-Uvssa-E2-Ubiquitin Complex. within 5.0Å range: probe atom residue distance (Å) B Occ R:Zn202 b:632.1 occ:1.00 HD1 R:HIS77 1.5 526.7 1.0 OD1 R:ASP97 2.0 533.2 1.0 OD2 R:ASP97 2.0 533.2 1.0 HB2 R:CYS75 2.0 501.3 1.0 ND1 R:HIS77 2.0 526.7 1.0 CG R:ASP97 2.1 533.2 1.0 SG R:CYS94 2.4 542.2 1.0 CB R:CYS75 2.4 501.3 1.0 SG R:CYS75 2.5 501.3 1.0 HB3 R:CYS75 2.6 501.3 1.0 HB2 R:HIS77 2.8 526.7 1.0 CE1 R:HIS77 2.9 526.7 1.0 CG R:HIS77 2.9 526.7 1.0 HE1 R:HIS77 3.1 526.7 1.0 CB R:HIS77 3.4 526.7 1.0 H R:ASP97 3.4 533.2 1.0 CB R:ASP97 3.5 533.2 1.0 HB2 R:CYS94 3.5 542.2 1.0 CB R:CYS94 3.5 542.2 1.0 HB3 R:ASP97 3.7 533.2 1.0 HB3 R:CYS94 3.7 542.2 1.0 H R:CYS75 3.8 501.3 1.0 H R:HIS77 3.8 526.7 1.0 NE2 R:HIS77 3.9 526.7 1.0 HB3 R:HIS77 3.9 526.7 1.0 CA R:CYS75 3.9 501.3 1.0 CD2 R:HIS77 3.9 526.7 1.0 HB2 R:ASP97 4.1 533.2 1.0 N R:ASP97 4.2 533.2 1.0 HE2 R:PHE79 4.2 507.8 1.0 HB2 R:LEU96 4.2 546.0 1.0 N R:CYS75 4.3 501.3 1.0 CA R:ASP97 4.4 533.2 1.0 HA R:CYS75 4.5 501.3 1.0 HA3 R:GLY73 4.5 479.7 1.0 N R:HIS77 4.5 526.7 1.0 CA R:HIS77 4.6 526.7 1.0 C R:CYS75 4.6 501.3 1.0 HB2 R:ARG99 4.7 470.9 1.0 HD2 R:HIS77 4.7 526.7 1.0 HE R:ARG99 4.8 470.9 1.0 O R:ASP97 4.9 533.2 1.0 H R:LEU96 4.9 546.0 1.0 C R:ASP97 4.9 533.2 1.0 CA R:CYS94 5.0 542.2 1.0 HB3 R:LEU96 5.0 546.0 1.0

Zinc binding site 3 out of 3 in the C(N)RL4CSA-Uvssa-E2-Ubiquitin Complex.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of C(N)RL4CSA-Uvssa-E2-Ubiquitin Complex. within 5.0Å range: probe atom residue distance (Å) B Occ R:Zn203 b:777.9 occ:1.00 HB3 R:CYS53 1.6 617.0 1.0 HB2 R:HIS82 1.8 625.3 1.0 HB2 R:CYS53 2.0 617.0 1.0 CB R:CYS53 2.0 617.0 1.0 ND1 R:HIS82 2.0 625.3 1.0 SG R:CYS56 2.3 600.0 1.0 SG R:CYS68 2.4 575.2 1.0 CB R:HIS82 2.5 625.3 1.0 SG R:CYS53 2.5 617.0 1.0 CG R:HIS82 2.5 625.3 1.0 HB3 R:HIS82 2.9 625.3 1.0 CE1 R:HIS82 3.3 625.3 1.0 HB2 R:CYS56 3.4 600.0 1.0 H R:HIS82 3.5 625.3 1.0 CA R:CYS53 3.5 617.0 1.0 CB R:CYS56 3.5 600.0 1.0 H R:CYS53 3.5 617.0 1.0 H R:CYS56 3.6 600.0 1.0 HB2 R:CYS68 3.7 575.2 1.0 CB R:CYS68 3.7 575.2 1.0 HB3 R:HIS80 3.7 542.5 1.0 HE1 R:HIS82 3.7 625.3 1.0 CA R:HIS82 3.8 625.3 1.0 CD2 R:HIS82 3.8 625.3 1.0 N R:CYS53 4.0 617.0 1.0 N R:HIS82 4.0 625.3 1.0 HA R:CYS53 4.1 617.0 1.0 NE2 R:HIS82 4.1 625.3 1.0 HB3 R:CYS56 4.2 600.0 1.0 N R:CYS56 4.2 600.0 1.0 C R:CYS53 4.3 617.0 1.0 HA R:CYS68 4.4 575.2 1.0 HB2 R:GLU55 4.4 586.6 1.0 HB3 R:CYS68 4.4 575.2 1.0 HA R:HIS82 4.4 625.3 1.0 HB2 R:HIS80 4.5 542.5 1.0 C R:HIS82 4.5 625.3 1.0 CA R:CYS56 4.5 600.0 1.0 CB R:HIS80 4.5 542.5 1.0 H R:CYS83 4.5 585.9 1.0 HD2 R:HIS82 4.6 625.3 1.0 CA R:CYS68 4.6 575.2 1.0 O R:CYS53 4.7 617.0 1.0 H R:GLU55 4.7 586.6 1.0 N R:CYS83 4.8 585.9 1.0 HA R:CYS56 4.8 600.0 1.0 HE2 R:HIS82 5.0 625.3 1.0

G.Kokic, G.Yakoub, D.Van Den Heuvel, A.P.Wondergem, P.J.Van Der Meer, Y.Van Der Weegen, A.Chernev, I.Fianu, T.J.Fokkens, S.Lorenz, H.Urlaub, P.Cramer, M.S.Luijsterburg. Structural Basis For Rna Polymerase II Ubiquitylation and Inactivation in Transcription-Coupled Repair. Nat.Struct.Mol.Biol. V. 31 536 2024.
ISSN: ESSN 1545-9985
PubMed: 38316879
DOI: 10.1038/S41594-023-01207-0