Zinc in PDB 7dws: The Structure of T4 Lysozyme I3C/C54T/R125C/E128C Complex with Zinc Ions

All present enzymatic activity of The Structure of T4 Lysozyme I3C/C54T/R125C/E128C Complex with Zinc Ions:
3.2.1.17;

The structure of The Structure of T4 Lysozyme I3C/C54T/R125C/E128C Complex with Zinc Ions, PDB code: 7dws was solved by X.Chen, S.Chen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.86 / 2.80
Space group	P 62 2 2
Cell size a, b, c (Å), α, β, γ (°)	102.861, 102.861, 244.533, 90, 90, 120
R / Rfree (%)	33 / 34.5

The binding sites of Zinc atom in the The Structure of T4 Lysozyme I3C/C54T/R125C/E128C Complex with Zinc Ions (pdb code 7dws). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the The Structure of T4 Lysozyme I3C/C54T/R125C/E128C Complex with Zinc Ions, PDB code: 7dws:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the The Structure of T4 Lysozyme I3C/C54T/R125C/E128C Complex with Zinc Ions


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The Structure of T4 Lysozyme I3C/C54T/R125C/E128C Complex with Zinc Ions within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:91.8 occ:1.00 SG A:CYS125 2.7 75.5 1.0 CB A:CYS125 4.2 75.5 1.0 SG A:CYS128 4.2 87.0 1.0

Zinc binding site 2 out of 4 in the The Structure of T4 Lysozyme I3C/C54T/R125C/E128C Complex with Zinc Ions


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of The Structure of T4 Lysozyme I3C/C54T/R125C/E128C Complex with Zinc Ions within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn201 b:86.1 occ:1.00 SG C:CYS125 2.7 90.4 1.0 SG B:CYS128 3.1 80.0 1.0 CB B:CYS128 3.4 79.8 1.0 N B:CYS128 3.4 79.5 1.0 CA B:CYS125 3.6 86.8 1.0 CB B:CYS125 3.8 85.5 1.0 SG B:CYS125 3.8 81.0 1.0 C B:CYS125 3.9 91.5 1.0 CA B:CYS128 4.0 80.0 1.0 N B:TRP126 4.0 93.9 1.0 CB C:CYS125 4.1 83.3 1.0 N B:ASP127 4.2 83.3 1.0 C B:ASP127 4.4 84.4 1.0 CA B:ASP127 4.6 83.9 1.0 O B:CYS125 4.6 94.8 1.0 CB B:ASP127 4.7 83.9 1.0 O B:LYS124 4.7 97.7 1.0 C B:TRP126 4.8 95.1 1.0 O C:HOH301 4.8 84.5 1.0 N B:CYS125 4.8 92.5 1.0 CB C:GLN123 4.9 84.6 1.0 ZN B:ZN202 5.0 79.6 1.0 SD C:MET120 5.0 94.9 1.0

Zinc binding site 3 out of 4 in the The Structure of T4 Lysozyme I3C/C54T/R125C/E128C Complex with Zinc Ions


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of The Structure of T4 Lysozyme I3C/C54T/R125C/E128C Complex with Zinc Ions within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn202 b:79.6 occ:1.00 SG B:CYS128 2.5 80.0 1.0 SG C:CYS128 2.7 82.7 1.0 CB B:CYS128 3.7 79.8 1.0 CB C:CYS128 3.9 82.8 1.0 CE C:MET120 4.4 83.6 1.0 SG B:CYS125 4.6 81.0 1.0 ZN C:ZN201 4.6 78.2 1.0 SD B:MET120 4.8 89.6 1.0 ZN B:ZN201 5.0 86.1 1.0 CA B:CYS128 5.0 80.0 1.0

Zinc binding site 4 out of 4 in the The Structure of T4 Lysozyme I3C/C54T/R125C/E128C Complex with Zinc Ions


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of The Structure of T4 Lysozyme I3C/C54T/R125C/E128C Complex with Zinc Ions within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn201 b:78.2 occ:1.00 SG C:CYS128 2.7 82.7 1.0 CB C:CYS128 3.2 82.8 1.0 SG C:CYS125 3.7 90.4 1.0 N C:CYS128 3.7 82.8 1.0 CB C:CYS125 3.8 83.3 1.0 CA C:CYS125 3.9 84.2 1.0 CA C:CYS128 4.1 83.3 1.0 C C:CYS125 4.3 85.3 1.0 N C:TRP126 4.5 85.9 1.0 ZN B:ZN202 4.6 79.6 1.0 N C:ASP127 4.7 88.1 1.0 C C:ASP127 4.8 89.4 1.0 O C:HOH301 4.9 84.5 1.0 O C:CYS125 4.9 97.7 1.0

X.Chen, B.Tan, S.Wang, R.Tang, Z.Bao, G.Chen, S.Chen, W.Tang, Z.Wang, C.Long, W.W.Lu, D.Yang, L.Bian, S.Peng. Rationally Designed Protein Cross-Linked Hydrogel For Bone Regeneration Via Synergistic Release of Magnesium and Zinc Ions. Biomaterials V. 274 20895 2021.
ISSN: ISSN 1878-5905
PubMed: 34020269
DOI: 10.1016/J.BIOMATERIALS.2021.120895