Zinc in PDB 6xjd: Two Mouse Cgas Catalytic Domain Binding to Human Assembled Nucleosome

All present enzymatic activity of Two Mouse Cgas Catalytic Domain Binding to Human Assembled Nucleosome:
2.7.7.86;

The binding sites of Zinc atom in the Two Mouse Cgas Catalytic Domain Binding to Human Assembled Nucleosome (pdb code 6xjd). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Two Mouse Cgas Catalytic Domain Binding to Human Assembled Nucleosome, PDB code: 6xjd:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Two Mouse Cgas Catalytic Domain Binding to Human Assembled Nucleosome


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Two Mouse Cgas Catalytic Domain Binding to Human Assembled Nucleosome within 5.0Å range: probe atom residue distance (Å) B Occ K:Zn601 b:0.8 occ:1.00 CE K:LYS395 2.7 0.4 1.0 CE K:LYS391 2.8 0.2 1.0 NZ K:LYS395 2.9 0.4 1.0 O K:CYS385 3.1 0.0 1.0 CA K:CYS385 3.1 0.0 1.0 CB K:CYS385 3.2 0.0 1.0 C K:CYS385 3.5 0.0 1.0 NZ K:LYS391 3.7 0.2 1.0 CD K:LYS391 3.7 0.2 1.0 CD K:LYS395 3.9 0.4 1.0 SG K:CYS385 4.1 0.0 1.0 N K:CYS385 4.4 0.0 1.0 CG K:LYS395 4.5 0.4 1.0 N K:GLU386 4.7 0.3 1.0 CB K:LYS395 5.0 0.4 1.0

Zinc binding site 2 out of 2 in the Two Mouse Cgas Catalytic Domain Binding to Human Assembled Nucleosome


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Two Mouse Cgas Catalytic Domain Binding to Human Assembled Nucleosome within 5.0Å range: probe atom residue distance (Å) B Occ L:Zn601 b:0.8 occ:1.00 CE L:LYS395 2.7 0.4 1.0 CE L:LYS391 2.8 0.2 1.0 NZ L:LYS395 2.9 0.4 1.0 O L:CYS385 3.1 0.0 1.0 CA L:CYS385 3.1 0.0 1.0 CB L:CYS385 3.2 0.0 1.0 C L:CYS385 3.5 0.0 1.0 NZ L:LYS391 3.7 0.2 1.0 CD L:LYS391 3.7 0.2 1.0 CD L:LYS395 3.9 0.4 1.0 SG L:CYS385 4.1 0.0 1.0 N L:CYS385 4.4 0.0 1.0 CG L:LYS395 4.5 0.4 1.0 N L:GLU386 4.7 0.3 1.0 CB L:LYS395 5.0 0.4 1.0

B.Zhao, P.Xu, C.M.Rowlett, T.Jing, O.Shinde, Y.Lei, A.P.West, W.R.Liu, P.Li. The Molecular Basis of Tight Nuclear Tethering and Inactivation of Cgas. Nature V. 587 673 2020.
ISSN: ESSN 1476-4687
PubMed: 32911481
DOI: 10.1038/S41586-020-2749-Z