Zinc in PDB 6xh8: Cuer-Transcription Activation Complex with Rna Transcript

All present enzymatic activity of Cuer-Transcription Activation Complex with Rna Transcript:
2.7.7.6;

The structure of Cuer-Transcription Activation Complex with Rna Transcript also contains other interesting chemical elements:

Copper

(Cu)

2 atoms

The binding sites of Zinc atom in the Cuer-Transcription Activation Complex with Rna Transcript (pdb code 6xh8). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cuer-Transcription Activation Complex with Rna Transcript, PDB code: 6xh8:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Cuer-Transcription Activation Complex with Rna Transcript


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cuer-Transcription Activation Complex with Rna Transcript within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1501 b:203.7 occ:1.00 HB2 D:CYS70 1.9 189.3 1.0 HB3 D:CYS85 1.9 197.2 1.0 HG D:CYS85 1.9 197.2 1.0 H D:LEU71 2.0 170.9 1.0 HG D:CYS88 2.1 186.2 1.0 SG D:CYS88 2.4 186.2 1.0 CB D:CYS85 2.5 197.2 1.0 SG D:CYS85 2.6 197.2 1.0 CB D:CYS70 2.8 189.3 1.0 N D:LEU71 2.8 170.9 1.0 H D:CYS72 2.8 186.4 1.0 HB2 D:CYS85 2.8 197.2 1.0 HB3 D:LEU71 3.2 170.9 1.0 SG D:CYS70 3.3 189.3 1.0 HB3 D:CYS70 3.4 189.3 1.0 CA D:CYS70 3.6 189.3 1.0 H D:CYS88 3.6 186.2 1.0 C D:CYS70 3.6 189.3 1.0 N D:CYS72 3.6 186.4 1.0 O D:CYS85 3.7 197.2 1.0 HB D:VAL90 3.7 176.9 1.0 CA D:LEU71 3.7 170.9 1.0 HA D:CYS70 3.7 189.3 1.0 CB D:LEU71 3.8 170.9 1.0 HB2 D:LEU71 3.8 170.9 1.0 CA D:CYS85 3.8 197.2 1.0 HB3 D:CYS88 3.9 186.2 1.0 H D:VAL90 3.9 176.9 1.0 CB D:CYS88 3.9 186.2 1.0 H D:GLY89 4.0 184.8 1.0 C D:CYS85 4.2 197.2 1.0 HB3 D:LYS87 4.2 198.4 1.0 C D:LEU71 4.2 170.9 1.0 H D:CYS85 4.2 197.2 1.0 SG D:CYS72 4.2 186.4 1.0 H D:GLY73 4.4 188.5 1.0 N D:CYS88 4.4 186.2 1.0 HB3 D:CYS72 4.4 186.4 1.0 HA D:CYS85 4.5 197.2 1.0 HB2 D:CYS88 4.5 186.2 1.0 N D:CYS85 4.5 197.2 1.0 HA D:LEU71 4.6 170.9 1.0 CB D:VAL90 4.6 176.9 1.0 H D:LYS74 4.6 193.6 1.0 HG21 D:VAL90 4.7 176.9 1.0 CB D:CYS72 4.7 186.4 1.0 HB3 D:LYS74 4.7 193.6 1.0 N D:VAL90 4.7 176.9 1.0 CA D:CYS72 4.7 186.4 1.0 O D:CYS70 4.7 189.3 1.0 CA D:CYS88 4.8 186.2 1.0 N D:GLY89 4.8 184.8 1.0 O D:VAL90 4.8 176.9 1.0 HG23 D:VAL90 4.8 176.9 1.0 HD2 D:TYR75 4.9 195.9 1.0 CG2 D:VAL90 4.9 176.9 1.0 N D:CYS70 4.9 189.3 1.0

Zinc binding site 2 out of 2 in the Cuer-Transcription Activation Complex with Rna Transcript


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cuer-Transcription Activation Complex with Rna Transcript within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1502 b:117.1 occ:1.00 HB3 D:CYS814 1.8 107.1 1.0 HB2 D:CYS888 2.0 103.5 1.0 HA D:CYS888 2.3 103.5 1.0 CB D:CYS888 2.4 103.5 1.0 SG D:CYS898 2.4 102.2 1.0 SG D:CYS888 2.4 103.5 1.0 SG D:CYS895 2.5 101.5 1.0 CB D:CYS814 2.5 107.1 1.0 SG D:CYS814 2.6 107.1 1.0 HB2 D:CYS898 2.7 102.2 1.0 CA D:CYS888 2.8 103.5 1.0 HB2 D:CYS814 3.0 107.1 1.0 CB D:CYS898 3.1 102.2 1.0 H D:CYS814 3.2 107.1 1.0 HB3 D:CYS895 3.3 101.5 1.0 HB3 D:CYS888 3.3 103.5 1.0 HH22 D:ARG883 3.3 111.7 1.0 CB D:CYS895 3.5 101.5 1.0 H D:CYS895 3.5 101.5 1.0 HB3 D:CYS898 3.6 102.2 1.0 HG1 D:THR816 3.6 113.0 1.0 H D:ASP889 3.7 107.3 1.0 CA D:CYS814 3.7 107.1 1.0 NH2 D:ARG883 3.8 111.7 1.0 N D:CYS888 3.8 103.5 1.0 N D:CYS814 3.8 107.1 1.0 H D:CYS898 4.0 102.2 1.0 C D:CYS888 4.0 103.5 1.0 H D:CYS888 4.0 103.5 1.0 HH12 D:ARG883 4.1 111.7 1.0 HH21 D:ARG883 4.1 111.7 1.0 OG1 D:THR816 4.1 113.0 1.0 N D:ASP889 4.1 107.3 1.0 HA D:CYS814 4.2 107.1 1.0 HB2 D:CYS895 4.2 101.5 1.0 N D:CYS895 4.2 101.5 1.0 HG13 D:VAL894 4.3 95.9 1.0 CA D:CYS898 4.4 102.2 1.0 CA D:CYS895 4.4 101.5 1.0 CZ D:ARG883 4.4 111.7 1.0 NH1 D:ARG883 4.5 111.7 1.0 N D:CYS898 4.5 102.2 1.0 HG21 D:THR816 4.5 113.0 1.0 O D:SER884 4.5 106.3 1.0 HA D:VAL885 4.6 90.8 1.0 O D:CYS895 4.7 101.5 1.0 C D:SER887 4.7 109.2 1.0 HA D:CYS898 4.7 102.2 1.0 OG1 D:THR890 4.8 103.3 1.0 HG23 D:THR816 4.9 113.0 1.0 C D:CYS895 4.9 101.5 1.0 C D:CYS814 4.9 107.1 1.0 HG1 D:THR890 4.9 103.3 1.0 H D:THR816 5.0 113.0 1.0 H D:THR890 5.0 103.3 1.0

W.Shi, B.Zhang, Y.Jiang, C.Liu, W.Zhou, M.Chen, Y.Yang, Y.Hu, B.Liu. Structural Basis of Cuer-Dependent Transcription Activation Iscience 2021.
ISSN: ESSN 2589-0042