Zinc in PDB 6xh7: Cuer-Tac Without Rna

All present enzymatic activity of Cuer-Tac Without Rna:
2.7.7.6;

The structure of Cuer-Tac Without Rna also contains other interesting chemical elements:

Copper

(Cu)

2 atoms

The binding sites of Zinc atom in the Cuer-Tac Without Rna (pdb code 6xh7). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cuer-Tac Without Rna, PDB code: 6xh7:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Cuer-Tac Without Rna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cuer-Tac Without Rna within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1501 b:205.5 occ:1.00 H D:CYS72 1.7 162.8 1.0 HG D:CYS85 1.8 156.7 1.0 SG D:CYS72 2.4 162.8 1.0 SG D:CYS70 2.4 156.6 1.0 N D:CYS72 2.4 162.8 1.0 H D:GLY73 2.5 162.5 1.0 H D:LYS74 2.9 159.1 1.0 HB2 D:CYS70 2.9 156.6 1.0 SG D:CYS85 2.9 156.7 1.0 H D:LEU71 3.0 141.7 1.0 CB D:CYS72 3.1 162.8 1.0 CA D:CYS72 3.1 162.8 1.0 N D:GLY73 3.2 162.5 1.0 HB3 D:CYS72 3.2 162.8 1.0 CB D:CYS70 3.2 156.6 1.0 N D:LEU71 3.2 141.7 1.0 HB3 D:LEU71 3.3 141.7 1.0 C D:LEU71 3.5 141.7 1.0 HG D:CYS88 3.5 143.9 1.0 C D:CYS72 3.6 162.8 1.0 CA D:LEU71 3.7 141.7 1.0 N D:LYS74 3.7 159.1 1.0 HB2 D:LYS74 3.8 159.1 1.0 C D:CYS70 3.8 156.6 1.0 HB3 D:CYS85 3.8 156.7 1.0 SG D:CYS88 3.8 143.9 1.0 CB D:CYS85 3.9 156.7 1.0 HB2 D:CYS85 3.9 156.7 1.0 HB3 D:LYS74 4.0 159.1 1.0 CB D:LEU71 4.0 141.7 1.0 HB3 D:CYS70 4.0 156.6 1.0 HB2 D:CYS72 4.0 162.8 1.0 HA D:CYS72 4.0 162.8 1.0 CA D:CYS70 4.1 156.6 1.0 CB D:LYS74 4.3 159.1 1.0 CA D:GLY73 4.3 162.5 1.0 HD3 D:LYS87 4.5 153.8 1.0 HB2 D:LEU71 4.5 141.7 1.0 HB3 D:LYS87 4.5 153.8 1.0 C D:GLY73 4.5 162.5 1.0 O D:LEU71 4.5 141.7 1.0 O D:CYS70 4.6 156.6 1.0 HA2 D:GLY73 4.6 162.5 1.0 HZ3 D:LYS74 4.6 159.1 1.0 HB3 D:CYS88 4.6 143.9 1.0 CA D:LYS74 4.6 159.1 1.0 HA D:LEU71 4.7 141.7 1.0 HB D:VAL90 4.7 143.2 1.0 HA D:CYS70 4.8 156.6 1.0 O D:CYS72 4.8 162.8 1.0 H D:CYS70 4.8 156.6 1.0 HZ2 D:LYS74 4.8 159.1 1.0 H D:CYS88 4.9 143.9 1.0 H D:TYR75 4.9 163.0 1.0 CB D:CYS88 5.0 143.9 1.0 HG D:LEU71 5.0 141.7 1.0

Zinc binding site 2 out of 2 in the Cuer-Tac Without Rna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cuer-Tac Without Rna within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1502 b:109.8 occ:1.00 HB2 D:CYS888 1.9 100.7 1.0 HA D:CYS888 2.1 100.7 1.0 CB D:CYS888 2.3 100.7 1.0 HB3 D:CYS814 2.3 105.2 1.0 SG D:CYS895 2.4 99.9 1.0 SG D:CYS814 2.4 105.2 1.0 SG D:CYS898 2.4 99.9 1.0 SG D:CYS888 2.4 100.7 1.0 CA D:CYS888 2.6 100.7 1.0 CB D:CYS814 2.8 105.2 1.0 HB2 D:CYS898 2.9 99.9 1.0 HB3 D:CYS888 3.2 100.7 1.0 CB D:CYS898 3.3 99.9 1.0 HB2 D:CYS814 3.3 105.2 1.0 HH22 D:ARG883 3.4 104.6 1.0 H D:CYS814 3.4 105.2 1.0 HB3 D:CYS895 3.5 99.9 1.0 H D:CYS895 3.5 99.9 1.0 N D:CYS888 3.6 100.7 1.0 CB D:CYS895 3.6 99.9 1.0 NH2 D:ARG883 3.7 104.6 1.0 HB3 D:CYS898 3.7 99.9 1.0 H D:ASP889 3.8 104.0 1.0 H D:CYS888 3.8 100.7 1.0 C D:CYS888 3.8 100.7 1.0 HH21 D:ARG883 3.8 104.6 1.0 CA D:CYS814 4.1 105.2 1.0 N D:CYS814 4.1 105.2 1.0 HG1 D:THR816 4.1 108.3 1.0 N D:ASP889 4.1 104.0 1.0 H D:CYS898 4.2 99.9 1.0 OG1 D:THR816 4.2 108.3 1.0 N D:CYS895 4.2 99.9 1.0 HG13 D:VAL894 4.3 94.5 1.0 HB2 D:CYS895 4.3 99.9 1.0 H D:THR890 4.4 102.1 1.0 CZ D:ARG883 4.4 104.6 1.0 CA D:CYS895 4.4 99.9 1.0 HH12 D:ARG883 4.5 104.6 1.0 C D:SER887 4.5 99.4 1.0 CA D:CYS898 4.5 99.9 1.0 HA D:CYS814 4.6 105.2 1.0 HG21 D:THR816 4.7 108.3 1.0 O D:CYS895 4.7 99.9 1.0 O D:SER887 4.7 99.4 1.0 N D:CYS898 4.7 99.9 1.0 NH1 D:ARG883 4.7 104.6 1.0 O D:CYS888 4.7 100.7 1.0 OG1 D:THR890 4.8 102.1 1.0 HG23 D:THR816 4.8 108.3 1.0 HG1 D:THR890 4.8 102.1 1.0 O D:SER884 4.8 98.8 1.0 HA D:CYS898 4.9 99.9 1.0 C D:CYS895 4.9 99.9 1.0 H D:THR816 5.0 108.3 1.0

W.Shi, B.Zhang, Y.Jiang, C.Liu, W.Zhou, M.Chen, Y.Yang, Y.Hu, B.Liu. Structural Basis of Cuer-Dependent Transcription Activation Iscience 2021.
ISSN: ESSN 2589-0042