Zinc in PDB 6oha: Yeast Guanine Deaminase

All present enzymatic activity of Yeast Guanine Deaminase:
3.5.4.3;

The structure of Yeast Guanine Deaminase, PDB code: 6oha was solved by R.S.Shek, J.B.French, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.07 / 2.21
Space group	P 43 2 2
Cell size a, b, c (Å), α, β, γ (°)	106.812, 106.812, 114.178, 90.00, 90.00, 90.00
R / Rfree (%)	15.6 / 20.3

The binding sites of Zinc atom in the Yeast Guanine Deaminase (pdb code 6oha). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Yeast Guanine Deaminase, PDB code: 6oha:

Zinc binding site 1 out of 1 in the Yeast Guanine Deaminase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Yeast Guanine Deaminase within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn502 b:41.8 occ:1.00 NE2 A:HIS100 2.0 35.3 1.0 NE2 A:HIS102 2.1 30.5 1.0 NE2 A:HIS258 2.2 41.8 1.0 OD1 A:ASP348 2.4 25.1 1.0 C2 A:XAN501 2.8 37.7 1.0 N1 A:XAN501 2.8 36.6 1.0 CD2 A:HIS102 2.9 23.2 1.0 O2 A:XAN501 2.9 48.4 1.0 CE1 A:HIS100 3.0 31.4 1.0 CD2 A:HIS258 3.0 28.4 1.0 HD2 A:HIS258 3.0 34.0 1.0 HD2 A:HIS102 3.0 27.8 1.0 CD2 A:HIS100 3.1 29.6 1.0 HE1 A:HIS100 3.1 37.6 1.0 CG A:ASP348 3.1 29.4 1.0 CE1 A:HIS102 3.2 26.9 1.0 HD2 A:HIS100 3.3 35.5 1.0 CE1 A:HIS258 3.3 44.0 1.0 OD2 A:ASP348 3.4 27.8 1.0 HE1 A:HIS102 3.5 32.2 1.0 N3 A:XAN501 3.5 40.3 1.0 C6 A:XAN501 3.5 42.4 1.0 HE1 A:HIS258 3.6 52.9 1.0 O A:HOH693 3.8 28.5 1.0 NE2 A:HIS297 4.0 29.2 1.0 ND1 A:HIS100 4.1 41.0 1.0 CG A:HIS102 4.1 26.3 1.0 C4 A:XAN501 4.1 53.4 1.0 C5 A:XAN501 4.2 48.2 1.0 CG A:HIS100 4.2 28.1 1.0 CG A:HIS258 4.2 33.8 1.0 ND1 A:HIS102 4.2 25.6 1.0 O6 A:XAN501 4.3 30.0 1.0 ND1 A:HIS258 4.3 43.1 1.0 HA A:ASP348 4.3 36.5 1.0 CB A:ASP348 4.4 27.1 1.0 HB2 A:ASP348 4.6 32.5 1.0 HB1 A:ALA296 4.6 35.8 1.0 CE1 A:HIS297 4.8 30.2 1.0 HE1 A:HIS297 4.8 36.3 1.0 HB3 A:ALA296 4.8 35.8 1.0 HD1 A:HIS100 4.8 49.1 1.0 CD2 A:HIS297 4.9 30.1 1.0 CA A:ASP348 4.9 30.5 1.0 HD2 A:HIS297 4.9 36.1 1.0 HE22 A:GLN105 4.9 28.7 1.0

R.Shek, T.Hilaire, J.Sim, J.B.French. Structural Determinants For Substrate Selectivity in Guanine Deaminase Enzymes of the Amidohydrolase Superfamily. Biochemistry V. 58 3280 2019.
ISSN: ISSN 0006-2960
PubMed: 31283204
DOI: 10.1021/ACS.BIOCHEM.9B00341