Atomistry » Zinc » PDB 8oel-8oq9 » 8oo8
Atomistry »
  Zinc »
    PDB 8oel-8oq9 »
      8oo8 »

Zinc in PDB 8oo8: Three-Dimensional Structure of Human Carbonic Anhydrase II in Complex with A Covalent Inhibitor

Enzymatic activity of Three-Dimensional Structure of Human Carbonic Anhydrase II in Complex with A Covalent Inhibitor

All present enzymatic activity of Three-Dimensional Structure of Human Carbonic Anhydrase II in Complex with A Covalent Inhibitor:
4.2.1.1;

Protein crystallography data

The structure of Three-Dimensional Structure of Human Carbonic Anhydrase II in Complex with A Covalent Inhibitor, PDB code: 8oo8 was solved by J.Leitans, K.Tars, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 70.50 / 1.40
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 42.45, 41.57, 72.79, 90, 104.4, 90
R / Rfree (%) 18.5 / 21.5

Other elements in 8oo8:

The structure of Three-Dimensional Structure of Human Carbonic Anhydrase II in Complex with A Covalent Inhibitor also contains other interesting chemical elements:

Fluorine (F) 3 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Three-Dimensional Structure of Human Carbonic Anhydrase II in Complex with A Covalent Inhibitor (pdb code 8oo8). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Three-Dimensional Structure of Human Carbonic Anhydrase II in Complex with A Covalent Inhibitor, PDB code: 8oo8:

Zinc binding site 1 out of 1 in 8oo8

Go back to Zinc Binding Sites List in 8oo8
Zinc binding site 1 out of 1 in the Three-Dimensional Structure of Human Carbonic Anhydrase II in Complex with A Covalent Inhibitor


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Three-Dimensional Structure of Human Carbonic Anhydrase II in Complex with A Covalent Inhibitor within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn301

b:15.9
occ:1.00
 N4 A:VV8302 2.0 10.2 1.0
ND1 A:HIS119 2.0 6.9 1.0
NE2 A:HIS94 2.0 7.0 1.0
NE2 A:HIS96 2.1 7.2 1.0
F13 A:VV8302 2.4 14.3 1.0
CE1 A:HIS119 2.9 6.6 1.0
C12 A:VV8302 2.9 14.0 1.0
CE1 A:HIS94 3.0 7.4 1.0
S1 A:VV8302 3.0 10.2 1.0
CD2 A:HIS96 3.1 7.1 1.0
CD2 A:HIS94 3.1 6.8 1.0
CE1 A:HIS96 3.1 8.2 1.0
CG A:HIS119 3.1 5.9 1.0
C7 A:VV8302 3.3 13.0 1.0
O2 A:VV8302 3.4 10.8 1.0
CB A:HIS119 3.6 5.5 1.0
OE1 A:GLU106 3.8 7.0 1.0
OG1 A:THR199 3.9 5.3 1.0
C11 A:VV8302 4.0 17.3 1.0
NE2 A:HIS119 4.1 5.9 1.0
ND1 A:HIS94 4.1 6.1 1.0
CG A:HIS96 4.2 6.4 1.0
CD2 A:HIS119 4.2 5.8 1.0
CG A:HIS94 4.2 6.2 1.0
ND1 A:HIS96 4.2 6.3 1.0
O3 A:VV8302 4.3 10.3 1.0
F15 A:VV8302 4.4 18.0 1.0
C8 A:VV8302 4.5 15.7 1.0
CD A:GLU106 4.8 5.8 1.0

Reference:

J.Leitans, K.Tars. Three-Dimensional Structure of Human Carbonic Anhydrase II in Complex with A Covalent Inhibitor To Be Published.
Page generated: Thu Oct 31 08:52:32 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy