Zinc in PDB 8olm: Carbonic Anhydrase 2 in Complex with STERIOD_SULPHAMOYL AKI1

All present enzymatic activity of Carbonic Anhydrase 2 in Complex with STERIOD_SULPHAMOYL AKI1:
4.2.1.1;

The structure of Carbonic Anhydrase 2 in Complex with STERIOD_SULPHAMOYL AKI1, PDB code: 8olm was solved by J.Brynda, P.M.Rezacova, E.Kudova, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	31.96 / 1.50
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	42.13, 41.17, 72.33, 90, 104.44, 90
R / Rfree (%)	18.2 / 19.7

The binding sites of Zinc atom in the Carbonic Anhydrase 2 in Complex with STERIOD_SULPHAMOYL AKI1 (pdb code 8olm). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Carbonic Anhydrase 2 in Complex with STERIOD_SULPHAMOYL AKI1, PDB code: 8olm:

Zinc binding site 1 out of 1 in the Carbonic Anhydrase 2 in Complex with STERIOD_SULPHAMOYL AKI1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Carbonic Anhydrase 2 in Complex with STERIOD_SULPHAMOYL AKI1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn301 b:10.5 occ:1.00 N19 A:VSM302 2.0 14.0 1.0 NE2 A:HIS94 2.0 9.4 1.0 NE2 A:HIS96 2.0 10.6 1.0 ND1 A:HIS119 2.1 9.1 1.0 CE1 A:HIS119 2.9 8.5 1.0 CD2 A:HIS94 3.0 10.3 1.0 CE1 A:HIS96 3.0 10.4 1.0 CE1 A:HIS94 3.0 9.3 1.0 CD2 A:HIS96 3.0 9.6 1.0 S22 A:VSM302 3.1 19.6 1.0 CG A:HIS119 3.1 9.0 1.0 O20 A:VSM302 3.2 18.9 1.0 CB A:HIS119 3.5 8.4 1.0 O3 A:VSM302 3.7 20.0 1.0 O A:HOH600 3.8 22.8 1.0 OG1 A:THR198 3.9 9.6 1.0 OE1 A:GLU106 3.9 11.4 1.0 CG A:HIS94 4.1 10.7 1.0 NE2 A:HIS119 4.1 10.1 1.0 ND1 A:HIS96 4.1 10.5 1.0 ND1 A:HIS94 4.1 11.7 1.0 CG A:HIS96 4.2 10.1 1.0 CD2 A:HIS119 4.2 9.9 1.0 O21 A:VSM302 4.3 19.4 1.0 CD A:GLU106 4.8 10.9 1.0 CA A:HIS119 5.0 8.4 1.0

J.Brynda, P.M.Rezacova, E.Kudova. Carbonic Anhydrase in Complex with STERIOD_SULPHAMOYL To Be Published.