Zinc in PDB 8oli: Carbonic Anhydrase 2 in Complex with STERIOD_SULPHAMOYL AKI_12

All present enzymatic activity of Carbonic Anhydrase 2 in Complex with STERIOD_SULPHAMOYL AKI_12:
4.2.1.1;

The structure of Carbonic Anhydrase 2 in Complex with STERIOD_SULPHAMOYL AKI_12, PDB code: 8oli was solved by J.Brynda, P.M.Rezacova, E.Kudova, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	25.25 / 1.40
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	42.087, 41.194, 72.052, 90, 104.33, 90
R / Rfree (%)	17.7 / 20

The binding sites of Zinc atom in the Carbonic Anhydrase 2 in Complex with STERIOD_SULPHAMOYL AKI_12 (pdb code 8oli). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Carbonic Anhydrase 2 in Complex with STERIOD_SULPHAMOYL AKI_12, PDB code: 8oli:

Zinc binding site 1 out of 1 in the Carbonic Anhydrase 2 in Complex with STERIOD_SULPHAMOYL AKI_12


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Carbonic Anhydrase 2 in Complex with STERIOD_SULPHAMOYL AKI_12 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn301 b:6.0 occ:1.00 NBA A:VRI302 2.0 8.1 1.0 NE2 A:HIS94 2.0 6.2 1.0 NE2 A:HIS96 2.0 6.4 1.0 ND1 A:HIS119 2.0 5.4 1.0 CE1 A:HIS119 2.9 5.2 1.0 CD2 A:HIS94 3.0 6.3 1.0 CE1 A:HIS96 3.0 6.3 1.0 CD2 A:HIS96 3.0 6.3 1.0 CE1 A:HIS94 3.0 6.1 1.0 SAX A:VRI302 3.1 9.1 1.0 CG A:HIS119 3.1 5.4 1.0 OAY A:VRI302 3.2 9.6 1.0 CB A:HIS119 3.5 5.2 1.0 OAW A:VRI302 3.7 13.8 1.0 O A:HOH625 3.7 16.9 1.0 OG1 A:THR198 3.9 5.7 1.0 OE1 A:GLU106 3.9 6.3 1.0 NE2 A:HIS119 4.1 5.3 1.0 ND1 A:HIS96 4.1 6.2 1.0 CG A:HIS94 4.1 6.6 1.0 ND1 A:HIS94 4.1 6.5 1.0 CG A:HIS96 4.2 6.2 1.0 CD2 A:HIS119 4.2 5.4 1.0 OAZ A:VRI302 4.3 10.7 1.0 CAB A:VRI302 4.7 17.8 1.0 CD A:GLU106 4.9 6.4 1.0 CA A:HIS119 5.0 5.3 1.0

J.Brynda, P.M.Rezacova, E.Kudova. Carbonic Anhydrase in Complex with STERIOD_SULPHAMOYL To Be Published.