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Zinc in PDB 8eof: Mycobacterium Tuberculosis Transcription Elongation Complex with Bacillus Subtilis Nusg (EC_PG)

Enzymatic activity of Mycobacterium Tuberculosis Transcription Elongation Complex with Bacillus Subtilis Nusg (EC_PG)

All present enzymatic activity of Mycobacterium Tuberculosis Transcription Elongation Complex with Bacillus Subtilis Nusg (EC_PG):
2.7.7.6;

Other elements in 8eof:

The structure of Mycobacterium Tuberculosis Transcription Elongation Complex with Bacillus Subtilis Nusg (EC_PG) also contains other interesting chemical elements:

Magnesium (Mg) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Mycobacterium Tuberculosis Transcription Elongation Complex with Bacillus Subtilis Nusg (EC_PG) (pdb code 8eof). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Mycobacterium Tuberculosis Transcription Elongation Complex with Bacillus Subtilis Nusg (EC_PG), PDB code: 8eof:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 8eof

Go back to Zinc Binding Sites List in 8eof
Zinc binding site 1 out of 2 in the Mycobacterium Tuberculosis Transcription Elongation Complex with Bacillus Subtilis Nusg (EC_PG)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Mycobacterium Tuberculosis Transcription Elongation Complex with Bacillus Subtilis Nusg (EC_PG) within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn2002

b:74.1
occ:1.00
SG D:CYS978 2.3 38.8 1.0
SG D:CYS975 2.3 31.5 1.0
SG D:CYS891 2.3 40.1 1.0
SG D:CYS968 2.3 14.7 1.0
CB D:CYS978 3.1 4.3 1.0
CB D:CYS975 3.5 0.0 1.0
CB D:CYS968 3.7 13.7 1.0
CB D:CYS891 3.7 28.0 1.0
CA D:CYS968 4.0 21.6 1.0
N D:CYS978 4.2 9.0 1.0
CA D:CYS978 4.3 0.0 1.0
N D:CYS975 4.3 2.5 1.0
N D:CYS891 4.3 27.1 1.0
N D:ALA969 4.4 30.1 1.0
CA D:CYS975 4.4 0.0 1.0
NH2 D:ARG963 4.5 28.8 1.0
OG1 D:THR970 4.5 25.3 1.0
CA D:CYS891 4.6 28.0 1.0
C D:CYS968 4.7 28.2 1.0
C D:CYS975 4.9 4.5 1.0
O D:CYS975 4.9 18.3 1.0
CG2 D:THR893 5.0 45.0 1.0

Zinc binding site 2 out of 2 in 8eof

Go back to Zinc Binding Sites List in 8eof
Zinc binding site 2 out of 2 in the Mycobacterium Tuberculosis Transcription Elongation Complex with Bacillus Subtilis Nusg (EC_PG)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Mycobacterium Tuberculosis Transcription Elongation Complex with Bacillus Subtilis Nusg (EC_PG) within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn2003

b:141.2
occ:1.00
SG D:CYS62 2.3 98.1 1.0
SG D:CYS60 2.3 84.5 1.0
SG D:CYS78 2.3 91.8 1.0
SG D:CYS75 2.3 99.6 1.0
CB D:CYS62 2.9 89.3 1.0
N D:CYS62 3.3 87.5 1.0
CB D:CYS78 3.3 85.0 1.0
CB D:CYS75 3.5 94.0 1.0
CA D:CYS62 3.5 88.0 1.0
CB D:CYS60 3.9 82.3 1.0
C D:CYS62 4.0 88.4 1.0
N D:CYS78 4.3 87.5 1.0
O D:CYS62 4.3 91.2 1.0
N D:TYR61 4.4 83.2 1.0
CG D:ARG77 4.4 94.0 1.0
C D:TYR61 4.5 84.7 1.0
CA D:CYS78 4.5 85.3 1.0
N D:GLY63 4.6 85.9 1.0
N D:LYS64 4.7 93.3 1.0
CB D:LYS64 4.8 94.2 1.0
NE D:ARG77 4.9 95.2 1.0
C D:CYS60 4.9 82.8 1.0
CA D:TYR61 4.9 83.6 1.0
CA D:CYS75 4.9 92.8 1.0

Reference:

R.K.Vishwakarma, M.Z.Qayyum, P.Babitzke, K.S.Murakami. Structural Basis of Nusg-Dependent Rna Polymerase Transcription Pausing in Bacteria To Be Published.
Page generated: Wed Oct 30 19:57:43 2024

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