Zinc in PDB 8eoe: Mycobacterium Tuberculosis Transcription Elongation Complex with Bacillus Subtilis Nusg (EC_LG)

All present enzymatic activity of Mycobacterium Tuberculosis Transcription Elongation Complex with Bacillus Subtilis Nusg (EC_LG):
2.7.7.6;

The structure of Mycobacterium Tuberculosis Transcription Elongation Complex with Bacillus Subtilis Nusg (EC_LG) also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Zinc atom in the Mycobacterium Tuberculosis Transcription Elongation Complex with Bacillus Subtilis Nusg (EC_LG) (pdb code 8eoe). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Mycobacterium Tuberculosis Transcription Elongation Complex with Bacillus Subtilis Nusg (EC_LG), PDB code: 8eoe:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Mycobacterium Tuberculosis Transcription Elongation Complex with Bacillus Subtilis Nusg (EC_LG)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Mycobacterium Tuberculosis Transcription Elongation Complex with Bacillus Subtilis Nusg (EC_LG) within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn2002 b:80.0 occ:1.00 SG D:CYS978 2.3 57.2 1.0 SG D:CYS975 2.3 56.9 1.0 SG D:CYS891 2.3 62.8 1.0 SG D:CYS968 2.3 58.5 1.0 CB D:CYS978 3.2 30.8 1.0 CB D:CYS975 3.6 29.7 1.0 CB D:CYS891 3.6 51.2 1.0 CB D:CYS968 3.7 42.4 1.0 CA D:CYS968 4.1 47.0 1.0 NH2 D:ARG963 4.2 42.9 1.0 N D:CYS978 4.3 36.5 1.0 CA D:CYS978 4.3 27.7 1.0 N D:CYS891 4.3 55.4 1.0 N D:ALA969 4.4 55.6 1.0 N D:CYS975 4.4 14.9 1.0 CA D:CYS975 4.5 24.8 1.0 OG1 D:THR970 4.6 52.2 1.0 CA D:CYS891 4.6 51.1 1.0 C D:CYS968 4.8 54.0 1.0 O D:CYS975 4.9 42.6 1.0 C D:CYS975 4.9 32.1 1.0 CG2 D:THR893 5.0 62.9 1.0

Zinc binding site 2 out of 2 in the Mycobacterium Tuberculosis Transcription Elongation Complex with Bacillus Subtilis Nusg (EC_LG)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Mycobacterium Tuberculosis Transcription Elongation Complex with Bacillus Subtilis Nusg (EC_LG) within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn2003 b:155.8 occ:1.00 SG D:CYS62 2.3 108.1 1.0 SG D:CYS60 2.3 98.9 1.0 SG D:CYS78 2.3 102.0 1.0 SG D:CYS75 2.3 98.3 1.0 CB D:CYS62 2.9 101.8 1.0 N D:CYS62 3.2 106.2 1.0 CB D:CYS78 3.4 101.8 1.0 CA D:CYS62 3.5 103.8 1.0 CB D:CYS75 3.6 100.0 1.0 CB D:CYS60 3.9 100.7 1.0 C D:CYS62 4.0 103.2 1.0 O D:CYS62 4.3 102.9 1.0 N D:CYS78 4.3 101.5 1.0 N D:TYR61 4.4 102.3 1.0 C D:TYR61 4.4 105.6 1.0 CG D:ARG77 4.5 113.3 1.0 CA D:CYS78 4.5 102.5 1.0 N D:GLY63 4.6 94.7 1.0 N D:LYS64 4.7 105.8 1.0 CA D:TYR61 4.8 102.9 1.0 CB D:LYS64 4.8 104.0 1.0 C D:CYS60 4.8 100.0 1.0 CA D:CYS75 5.0 102.1 1.0 NE D:ARG77 5.0 113.7 1.0 CB D:TYR61 5.0 102.4 1.0

R.K.Vishwakarma, M.Z.Qayyum, P.Babitzke, K.S.Murakami. Structural Basis of Nusg-Dependent Rna Polymerase Transcription Pausing in Bacteria To Be Published.