Zinc in PDB 7ysf: Crystal Structure of ZNF524 ZF1-4 in Complex with Telomeric Dna

The structure of Crystal Structure of ZNF524 ZF1-4 in Complex with Telomeric Dna, PDB code: 7ysf was solved by F.D.Li, Z.Y.Xu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	27.59 / 2.40
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	43.807, 52.194, 97.491, 90, 90, 90
R / Rfree (%)	21.8 / 25.3

The binding sites of Zinc atom in the Crystal Structure of ZNF524 ZF1-4 in Complex with Telomeric Dna (pdb code 7ysf). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Crystal Structure of ZNF524 ZF1-4 in Complex with Telomeric Dna, PDB code: 7ysf:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Crystal Structure of ZNF524 ZF1-4 in Complex with Telomeric Dna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of ZNF524 ZF1-4 in Complex with Telomeric Dna within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn302 b:49.1 occ:1.00 CE1 A:HIS136 2.2 49.4 1.0 NE2 A:HIS132 2.2 44.9 1.0 SG A:CYS119 2.3 55.9 1.0 SG A:CYS116 2.5 55.6 1.0 ND1 A:HIS136 2.9 48.0 1.0 CD2 A:HIS132 3.0 44.4 1.0 CB A:CYS119 3.2 55.0 1.0 CB A:CYS116 3.3 58.3 1.0 CE1 A:HIS132 3.3 43.4 1.0 NE2 A:HIS136 3.3 48.9 1.0 N A:CYS119 3.4 58.5 1.0 CA A:CYS119 3.9 58.0 1.0 CG A:HIS136 4.2 44.8 1.0 CG A:HIS132 4.2 41.1 1.0 CB A:VAL118 4.2 54.8 1.0 ND1 A:HIS132 4.3 41.2 1.0 CD2 A:HIS136 4.4 46.0 1.0 C A:VAL118 4.5 57.4 1.0 C A:CYS119 4.7 59.0 1.0 CA A:CYS116 4.8 60.9 1.0 CA A:VAL118 4.8 57.1 1.0 N A:LEU120 4.8 59.3 1.0 N A:VAL118 4.8 59.2 1.0 CG1 A:VAL118 4.8 53.4 1.0

Zinc binding site 2 out of 4 in the Crystal Structure of ZNF524 ZF1-4 in Complex with Telomeric Dna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of ZNF524 ZF1-4 in Complex with Telomeric Dna within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn303 b:24.2 occ:1.00 NE2 A:HIS164 2.1 30.0 1.0 NE2 A:HIS160 2.1 29.8 1.0 SG A:CYS144 2.3 27.1 1.0 SG A:CYS147 2.4 32.2 1.0 CD2 A:HIS164 3.0 30.1 1.0 CD2 A:HIS160 3.1 28.8 1.0 CE1 A:HIS164 3.1 29.0 1.0 CE1 A:HIS160 3.1 30.0 1.0 CB A:CYS144 3.2 30.6 1.0 CB A:CYS147 3.4 30.8 1.0 N A:CYS147 3.6 29.8 1.0 CA A:CYS147 4.1 30.0 1.0 ND1 A:HIS164 4.2 29.6 1.0 ND1 A:HIS160 4.2 29.3 1.0 CG A:HIS164 4.2 30.9 1.0 CB A:VAL146 4.2 30.9 1.0 CG A:HIS160 4.2 28.7 1.0 C A:VAL146 4.6 29.6 1.0 CA A:CYS144 4.6 32.1 1.0 CG1 A:VAL146 4.6 30.1 1.0 O A:CYS144 4.7 31.8 1.0 N A:GLY148 4.8 30.3 1.0 C A:CYS147 4.8 29.8 1.0 CA A:VAL146 4.8 30.1 1.0 N A:VAL146 4.9 30.8 1.0 C A:CYS144 4.9 31.7 1.0

Zinc binding site 3 out of 4 in the Crystal Structure of ZNF524 ZF1-4 in Complex with Telomeric Dna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of ZNF524 ZF1-4 in Complex with Telomeric Dna within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn304 b:26.1 occ:1.00 NE2 A:HIS192 2.1 33.4 1.0 NE2 A:HIS188 2.1 33.5 1.0 SG A:CYS172 2.2 30.7 1.0 SG A:CYS175 2.3 36.0 1.0 CD2 A:HIS188 2.9 32.1 1.0 CD2 A:HIS192 3.0 32.4 1.0 CE1 A:HIS192 3.1 32.9 1.0 CB A:CYS172 3.2 32.7 1.0 CE1 A:HIS188 3.2 33.7 1.0 CB A:CYS175 3.3 34.2 1.0 N A:CYS175 3.8 33.7 1.0 CA A:CYS175 4.1 34.2 1.0 CG A:HIS188 4.1 32.2 1.0 CG A:HIS192 4.2 33.3 1.0 ND1 A:HIS192 4.2 33.0 1.0 ND1 A:HIS188 4.3 33.1 1.0 C A:LEU174 4.3 34.5 1.0 CB A:LEU174 4.4 34.5 1.0 CA A:CYS172 4.6 32.7 1.0 C A:CYS175 4.7 34.4 1.0 CA A:LEU174 4.7 33.9 1.0 N A:LEU174 4.7 33.3 1.0 O A:CYS175 4.7 33.9 1.0 O A:HOH428 4.7 31.6 1.0 O A:LEU174 4.9 37.1 1.0

Zinc binding site 4 out of 4 in the Crystal Structure of ZNF524 ZF1-4 in Complex with Telomeric Dna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Crystal Structure of ZNF524 ZF1-4 in Complex with Telomeric Dna within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn305 b:34.8 occ:1.00 NE2 A:HIS221 2.0 37.3 1.0 NE2 A:HIS216 2.2 35.0 1.0 SG A:CYS203 2.3 38.5 1.0 SG A:CYS200 2.4 34.0 1.0 CB A:CYS203 2.8 36.4 1.0 CE1 A:HIS221 2.9 39.2 1.0 CD2 A:HIS221 3.0 38.2 1.0 CD2 A:HIS216 3.0 34.9 1.0 CB A:CYS200 3.2 35.9 1.0 CE1 A:HIS216 3.2 34.8 1.0 N A:CYS203 3.4 37.6 1.0 CA A:CYS203 3.7 38.8 1.0 ND1 A:HIS221 4.0 39.9 1.0 CG A:HIS221 4.1 39.6 1.0 CG A:HIS216 4.2 34.7 1.0 ND1 A:HIS216 4.3 35.2 1.0 C A:CYS203 4.5 39.2 1.0 C A:ILE202 4.6 42.6 1.0 CB A:ILE202 4.6 38.6 1.0 CA A:CYS200 4.7 35.3 1.0 N A:ARG204 4.8 38.9 1.0 CA A:ILE202 5.0 37.8 1.0 N A:ILE202 5.0 36.4 1.0 CB A:LYS220 5.0 39.1 1.0

F.D.Li, Z.Y.Xu. Crystal Structure of ZNF524 ZF1-4 in Complex with Telomeric Dna To Be Published.