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Zinc in PDB 7wsk: Crystal Structure of Sars-Cov-2 Omicron Spike Receptor-Binding Domain in Complex with Civet ACE2

Protein crystallography data

The structure of Crystal Structure of Sars-Cov-2 Omicron Spike Receptor-Binding Domain in Complex with Civet ACE2, PDB code: 7wsk was solved by B.Huang, P.Han, J.Qi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 20.66 / 3.30
Space group P 65 2 2
Cell size a, b, c (Å), α, β, γ (°) 152.665, 152.665, 187.116, 90, 90, 120
R / Rfree (%) 22.3 / 27.5

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of Sars-Cov-2 Omicron Spike Receptor-Binding Domain in Complex with Civet ACE2 (pdb code 7wsk). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Sars-Cov-2 Omicron Spike Receptor-Binding Domain in Complex with Civet ACE2, PDB code: 7wsk:

Zinc binding site 1 out of 1 in 7wsk

Go back to Zinc Binding Sites List in 7wsk
Zinc binding site 1 out of 1 in the Crystal Structure of Sars-Cov-2 Omicron Spike Receptor-Binding Domain in Complex with Civet ACE2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Sars-Cov-2 Omicron Spike Receptor-Binding Domain in Complex with Civet ACE2 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn704

b:161.9
occ:1.00
OE2 A:GLU402 2.0 72.8 1.0
NE2 A:HIS374 2.1 76.4 1.0
NE2 A:HIS378 2.1 70.1 1.0
CD A:GLU402 3.0 80.4 1.0
CD2 A:HIS374 3.0 69.3 1.0
CE1 A:HIS378 3.1 61.8 1.0
CD2 A:HIS378 3.1 59.3 1.0
CE1 A:HIS374 3.1 71.3 1.0
OE1 A:GLU402 3.3 94.3 1.0
OE2 A:GLU375 3.7 68.4 1.0
CG A:HIS374 4.2 60.7 1.0
ND1 A:HIS374 4.2 64.8 1.0
ND1 A:HIS378 4.2 50.4 1.0
CG A:HIS378 4.3 44.3 1.0
CG A:GLU402 4.3 61.6 1.0
CD A:GLU375 4.4 68.8 1.0
OE1 A:GLU375 4.5 73.8 1.0

Reference:

L.Li, P.Han, B.Huang, Y.Xie, W.Li, D.Zhang, P.Han, Z.Xu, B.Bai, J.Zhou, X.Kang, X.Li, A.Zheng, R.Zhang, S.Qiao, X.Zhao, J.Qi, Q.Wang, K.Liu, G.F.Gao. Broader-Species Receptor Binding and Structural Bases of Omicron Sars-Cov-2 to Both Mouse and Palm-Civet ACE2S. Cell Discov V. 8 65 2022.
ISSN: ESSN 2056-5968
PubMed: 35821014
DOI: 10.1038/S41421-022-00431-0
Page generated: Wed Oct 30 14:34:49 2024

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