Zinc in PDB 7syo: Structure of the Hcv Ires Bound to the 40S Ribosomal Subunit, Head Open. Structure 9(Delta Dii)

The binding sites of Zinc atom in the Structure of the Hcv Ires Bound to the 40S Ribosomal Subunit, Head Open. Structure 9(Delta Dii) (pdb code 7syo). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of the Hcv Ires Bound to the 40S Ribosomal Subunit, Head Open. Structure 9(Delta Dii), PDB code: 7syo:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of the Hcv Ires Bound to the 40S Ribosomal Subunit, Head Open. Structure 9(Delta Dii)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of the Hcv Ires Bound to the 40S Ribosomal Subunit, Head Open. Structure 9(Delta Dii) within 5.0Å range: probe atom residue distance (Å) B Occ b:Zn201 b:98.6 occ:1.00 CB b:CYS26 1.6 80.7 1.0 SG b:CYS77 2.2 74.8 1.0 SG b:CYS74 2.3 75.1 1.0 N b:CYS26 2.3 80.7 1.0 SG b:CYS23 2.3 79.3 1.0 SG b:CYS26 2.3 80.7 1.0 CA b:CYS26 2.3 80.7 1.0 CB b:CYS23 3.2 79.3 1.0 C b:CYS26 3.3 80.7 1.0 CB b:CYS77 3.3 74.8 1.0 C b:ASN25 3.4 77.0 1.0 O b:CYS26 3.8 80.7 1.0 CB b:CYS74 3.9 75.1 1.0 N b:ALA27 4.0 76.9 1.0 CB b:ASN25 4.1 77.0 1.0 CA b:ASN25 4.1 77.0 1.0 N b:ASN25 4.3 77.0 1.0 O b:ASN25 4.3 77.0 1.0 N b:ARG28 4.4 73.8 1.0 CB b:ARG28 4.5 73.8 1.0 CA b:CYS23 4.6 79.3 1.0 CA b:CYS77 4.7 74.8 1.0 N b:CYS74 4.7 75.1 1.0 C b:CYS23 4.9 79.3 1.0 CG b:ASN25 4.9 77.0 1.0 CA b:CYS74 4.9 75.1 1.0 N b:THR24 5.0 75.5 1.0

Zinc binding site 2 out of 2 in the Structure of the Hcv Ires Bound to the 40S Ribosomal Subunit, Head Open. Structure 9(Delta Dii)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of the Hcv Ires Bound to the 40S Ribosomal Subunit, Head Open. Structure 9(Delta Dii) within 5.0Å range: probe atom residue distance (Å) B Occ g:Zn200 b:740.7 occ:1.00 SG g:CYS141 2.3 646.3 1.0 SG g:CYS126 2.3 747.8 1.0 SG g:CYS144 2.3 666.7 1.0 SG g:CYS121 2.3 733.7 1.0 CB g:CYS144 3.1 666.7 1.0 CB g:CYS121 3.4 733.7 1.0 OG g:SER123 3.4 735.8 1.0 CB g:SER123 3.5 735.8 1.0 CB g:CYS141 3.9 646.3 1.0 CB g:CYS126 4.0 747.8 1.0 O g:CYS126 4.1 747.8 1.0 CA g:CYS144 4.4 666.7 1.0 N g:CYS126 4.5 747.8 1.0 N g:CYS144 4.5 666.7 1.0 N g:SER123 4.6 735.8 1.0 CA g:SER123 4.6 735.8 1.0 CA g:CYS126 4.7 747.8 1.0 N g:GLY142 4.7 647.2 1.0 CA g:CYS121 4.7 733.7 1.0 C g:CYS126 4.8 747.8 1.0 CA g:CYS141 4.9 646.3 1.0

Z.P.Brown, I.S.Abaeva, S.De, C.U.T.Hellen, T.V.Pestova, J.Frank. Molecular Architecture of 40S Translation Initiation Complexes on the Hepatitis C Virus Ires. Embo J. V. 41 10581 2022.
ISSN: ESSN 1460-2075
PubMed: 35822879
DOI: 10.15252/EMBJ.2022110581