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Atomistry » Zinc » PDB 7s6m-7spy » 7sgj » |
Zinc in PDB 7sgj: Crystal Structure of Danio Rerio Histone Deacetylase 10 in Complex with Dkfz-711Enzymatic activity of Crystal Structure of Danio Rerio Histone Deacetylase 10 in Complex with Dkfz-711
All present enzymatic activity of Crystal Structure of Danio Rerio Histone Deacetylase 10 in Complex with Dkfz-711:
3.5.1.48; 3.5.1.62; Protein crystallography data
The structure of Crystal Structure of Danio Rerio Histone Deacetylase 10 in Complex with Dkfz-711, PDB code: 7sgj
was solved by
C.J.Herbst-Gervasoni,
D.W.Christianson,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7sgj:
The structure of Crystal Structure of Danio Rerio Histone Deacetylase 10 in Complex with Dkfz-711 also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Danio Rerio Histone Deacetylase 10 in Complex with Dkfz-711
(pdb code 7sgj). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Danio Rerio Histone Deacetylase 10 in Complex with Dkfz-711, PDB code: 7sgj: Zinc binding site 1 out of 1 in 7sgjGo back to Zinc Binding Sites List in 7sgj
Zinc binding site 1 out
of 1 in the Crystal Structure of Danio Rerio Histone Deacetylase 10 in Complex with Dkfz-711
Mono view Stereo pair view
Reference:
R.R.Steimbach,
C.J.Herbst-Gervasoni,
S.Lechner,
T.M.Stewart,
G.Klinke,
J.Ridinger,
M.N.E.Geraldy,
G.Tihanyi,
J.R.Foley,
U.Uhrig,
B.Kuster,
G.Poschet,
R.A.Casero Jr.,
G.Medard,
I.Oehme,
D.W.Christianson,
N.Gunkel,
A.K.Miller.
Aza-Saha Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout. J.Am.Chem.Soc. V. 144 18861 2022.
Page generated: Sat Apr 8 03:09:39 2023
ISSN: ESSN 1520-5126 PubMed: 36200994 DOI: 10.1021/JACS.2C05030 |
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