Zinc in PDB 7qgj: Apo Structure of BIR2 Domain of BIRC2

All present enzymatic activity of Apo Structure of BIR2 Domain of BIRC2:
2.3.2.27;

The structure of Apo Structure of BIR2 Domain of BIRC2, PDB code: 7qgj was solved by A.Kraemer, F.Farges, M.P.Schwalm, K.Saxena, F.Preuss, S.Knapp, Structuralgenomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.81 / 1.30
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	87.241, 87.241, 59.625, 90, 90, 120
R / Rfree (%)	14.2 / 15.5

The binding sites of Zinc atom in the Apo Structure of BIR2 Domain of BIRC2 (pdb code 7qgj). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Apo Structure of BIR2 Domain of BIRC2, PDB code: 7qgj:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Apo Structure of BIR2 Domain of BIRC2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Apo Structure of BIR2 Domain of BIRC2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn301 b:20.4 occ:1.00 NE2 A:HIS240 2.1 19.5 1.0 SG A:CYS247 2.3 22.9 1.0 SG A:CYS223 2.3 21.3 1.0 SG A:CYS220 2.3 20.2 1.0 CE1 A:HIS240 2.9 19.6 1.0 CB A:CYS220 3.1 20.1 1.0 CB A:CYS247 3.2 21.7 1.0 CD2 A:HIS240 3.2 19.6 1.0 CB A:CYS223 3.2 21.0 1.0 N A:CYS223 3.6 20.5 1.0 CA A:CYS223 4.0 20.6 1.0 ND1 A:HIS240 4.1 19.7 1.0 CG A:HIS240 4.2 19.2 1.0 CA A:CYS247 4.4 22.0 1.0 CA A:CYS220 4.6 18.9 1.0 CB A:ALA222 4.7 20.1 1.0 C A:ALA222 4.7 20.5 1.0 CB A:PHE244 4.8 20.7 1.0 C A:CYS223 4.8 20.8 1.0 CB A:PHE249 4.8 22.7 1.0 N A:GLY224 4.9 21.8 1.0 N A:ALA222 5.0 19.2 1.0

Zinc binding site 2 out of 2 in the Apo Structure of BIR2 Domain of BIRC2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Apo Structure of BIR2 Domain of BIRC2 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn301 b:20.4 occ:1.00 NE2 B:HIS240 2.1 19.6 1.0 SG B:CYS247 2.3 21.7 1.0 SG B:CYS220 2.3 20.2 1.0 SG B:CYS223 2.3 21.2 1.0 CE1 B:HIS240 3.0 21.0 1.0 CB B:CYS220 3.1 19.0 1.0 CB B:CYS247 3.2 21.3 1.0 CD2 B:HIS240 3.2 19.2 1.0 CB B:CYS223 3.2 21.4 1.0 N B:CYS223 3.6 21.1 1.0 CA B:CYS223 4.0 20.8 1.0 ND1 B:HIS240 4.1 20.5 1.0 CG B:HIS240 4.3 19.3 1.0 CA B:CYS247 4.4 22.0 1.0 CB B:ALA222 4.5 21.3 1.0 C B:ALA222 4.5 20.5 1.0 CA B:CYS220 4.5 18.0 1.0 C B:CYS223 4.8 21.0 1.0 CB B:PHE244 4.8 19.9 1.0 N B:ALA222 4.8 19.4 1.0 CA B:ALA222 4.9 20.3 1.0 N B:GLY224 4.9 20.3 1.0 CB B:PHE249 5.0 24.5 1.0

A.Kraemer, F.Farges, M.P.Schwalm, K.Saxena, S.Knapp, Structural Genomics Consortium (Sgc). Apo Structure BIR2 Domain of BIRC2 To Be Published.