Zinc in PDB 7ouf: Structure of the Stlv Intasome:B56 Complex Bound to the Strand- Transfer Inhibitor XZ450
Other elements in 7ouf:
The structure of Structure of the Stlv Intasome:B56 Complex Bound to the Strand- Transfer Inhibitor XZ450 also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of the Stlv Intasome:B56 Complex Bound to the Strand- Transfer Inhibitor XZ450
(pdb code 7ouf). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the
Structure of the Stlv Intasome:B56 Complex Bound to the Strand- Transfer Inhibitor XZ450, PDB code: 7ouf:
Jump to Zinc binding site number:
1;
2;
3;
4;
Zinc binding site 1 out
of 4 in 7ouf
Go back to
Zinc Binding Sites List in 7ouf
Zinc binding site 1 out
of 4 in the Structure of the Stlv Intasome:B56 Complex Bound to the Strand- Transfer Inhibitor XZ450
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Structure of the Stlv Intasome:B56 Complex Bound to the Strand- Transfer Inhibitor XZ450 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Zn1000
b:75.8
occ:1.00
|
ND1
|
D:HIS12
|
2.0
|
35.1
|
1.0
|
NE2
|
D:HIS8
|
2.0
|
24.9
|
1.0
|
CE1
|
D:HIS12
|
2.1
|
35.1
|
1.0
|
SG
|
D:CYS35
|
2.3
|
67.9
|
1.0
|
SG
|
D:CYS38
|
2.3
|
71.8
|
1.0
|
CD2
|
D:HIS8
|
2.7
|
24.9
|
1.0
|
CB
|
D:CYS35
|
3.0
|
67.9
|
1.0
|
CE1
|
D:HIS8
|
3.1
|
24.9
|
1.0
|
CG
|
D:HIS12
|
3.2
|
35.1
|
1.0
|
NE2
|
D:HIS12
|
3.3
|
35.1
|
1.0
|
CB
|
D:CYS38
|
3.8
|
71.8
|
1.0
|
CD2
|
D:HIS12
|
3.8
|
35.1
|
1.0
|
CG
|
D:HIS8
|
3.9
|
24.9
|
1.0
|
ND1
|
D:HIS8
|
4.1
|
24.9
|
1.0
|
CB
|
D:HIS12
|
4.2
|
35.1
|
1.0
|
O
|
D:HIS8
|
4.4
|
24.9
|
1.0
|
CA
|
D:HIS12
|
4.4
|
35.1
|
1.0
|
CA
|
D:CYS35
|
4.5
|
67.9
|
1.0
|
N
|
D:CYS38
|
4.6
|
71.8
|
1.0
|
CA
|
D:CYS38
|
4.8
|
71.8
|
1.0
|
|
Zinc binding site 2 out
of 4 in 7ouf
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Zinc Binding Sites List in 7ouf
Zinc binding site 2 out
of 4 in the Structure of the Stlv Intasome:B56 Complex Bound to the Strand- Transfer Inhibitor XZ450
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Structure of the Stlv Intasome:B56 Complex Bound to the Strand- Transfer Inhibitor XZ450 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Zn301
b:40.4
occ:1.00
|
ND1
|
E:HIS12
|
2.0
|
10.8
|
1.0
|
NE2
|
E:HIS8
|
2.0
|
12.4
|
1.0
|
SG
|
E:CYS35
|
2.3
|
18.6
|
1.0
|
SG
|
E:CYS38
|
2.3
|
10.8
|
1.0
|
CE1
|
E:HIS12
|
2.6
|
10.8
|
1.0
|
CD2
|
E:HIS8
|
2.9
|
12.4
|
1.0
|
CE1
|
E:HIS8
|
3.0
|
12.4
|
1.0
|
CB
|
E:CYS35
|
3.1
|
18.6
|
1.0
|
CG
|
E:HIS12
|
3.3
|
10.8
|
1.0
|
CB
|
E:CYS38
|
3.4
|
10.8
|
1.0
|
NE2
|
E:HIS12
|
3.9
|
10.8
|
1.0
|
CB
|
E:HIS12
|
3.9
|
10.8
|
1.0
|
CG
|
E:HIS8
|
4.0
|
12.4
|
1.0
|
ND1
|
E:HIS8
|
4.0
|
12.4
|
1.0
|
N
|
E:CYS38
|
4.1
|
10.8
|
1.0
|
CD2
|
E:HIS12
|
4.2
|
10.8
|
1.0
|
CA
|
E:HIS12
|
4.2
|
10.8
|
1.0
|
CA
|
E:CYS38
|
4.3
|
10.8
|
1.0
|
O
|
E:HIS8
|
4.5
|
12.4
|
1.0
|
CA
|
E:CYS35
|
4.6
|
18.6
|
1.0
|
CB
|
E:ALA37
|
5.0
|
10.8
|
1.0
|
|
Zinc binding site 3 out
of 4 in 7ouf
Go back to
Zinc Binding Sites List in 7ouf
Zinc binding site 3 out
of 4 in the Structure of the Stlv Intasome:B56 Complex Bound to the Strand- Transfer Inhibitor XZ450
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of Structure of the Stlv Intasome:B56 Complex Bound to the Strand- Transfer Inhibitor XZ450 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn1000
b:74.1
occ:1.00
|
ND1
|
A:HIS12
|
2.0
|
39.2
|
1.0
|
NE2
|
A:HIS8
|
2.0
|
16.0
|
1.0
|
CE1
|
A:HIS12
|
2.1
|
39.2
|
1.0
|
SG
|
A:CYS35
|
2.3
|
59.7
|
1.0
|
SG
|
A:CYS38
|
2.3
|
61.2
|
1.0
|
CD2
|
A:HIS8
|
2.7
|
16.0
|
1.0
|
CB
|
A:CYS35
|
3.0
|
59.7
|
1.0
|
CE1
|
A:HIS8
|
3.1
|
16.0
|
1.0
|
CG
|
A:HIS12
|
3.2
|
39.2
|
1.0
|
NE2
|
A:HIS12
|
3.3
|
39.2
|
1.0
|
CB
|
A:CYS38
|
3.8
|
61.2
|
1.0
|
CD2
|
A:HIS12
|
3.8
|
39.2
|
1.0
|
CG
|
A:HIS8
|
3.9
|
16.0
|
1.0
|
ND1
|
A:HIS8
|
4.1
|
16.0
|
1.0
|
CB
|
A:HIS12
|
4.2
|
39.2
|
1.0
|
O
|
A:HIS8
|
4.4
|
16.0
|
1.0
|
CA
|
A:HIS12
|
4.4
|
39.2
|
1.0
|
CA
|
A:CYS35
|
4.5
|
59.7
|
1.0
|
N
|
A:CYS38
|
4.6
|
61.2
|
1.0
|
CA
|
A:CYS38
|
4.8
|
61.2
|
1.0
|
|
Zinc binding site 4 out
of 4 in 7ouf
Go back to
Zinc Binding Sites List in 7ouf
Zinc binding site 4 out
of 4 in the Structure of the Stlv Intasome:B56 Complex Bound to the Strand- Transfer Inhibitor XZ450
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of Structure of the Stlv Intasome:B56 Complex Bound to the Strand- Transfer Inhibitor XZ450 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn301
b:39.9
occ:1.00
|
ND1
|
B:HIS12
|
2.0
|
10.1
|
1.0
|
NE2
|
B:HIS8
|
2.0
|
12.5
|
1.0
|
SG
|
B:CYS35
|
2.3
|
23.5
|
1.0
|
SG
|
B:CYS38
|
2.3
|
10.8
|
1.0
|
CE1
|
B:HIS12
|
2.6
|
10.1
|
1.0
|
CD2
|
B:HIS8
|
2.9
|
12.5
|
1.0
|
CE1
|
B:HIS8
|
3.0
|
12.5
|
1.0
|
CB
|
B:CYS35
|
3.1
|
23.5
|
1.0
|
CG
|
B:HIS12
|
3.3
|
10.1
|
1.0
|
CB
|
B:CYS38
|
3.4
|
10.8
|
1.0
|
NE2
|
B:HIS12
|
3.9
|
10.1
|
1.0
|
CB
|
B:HIS12
|
3.9
|
10.1
|
1.0
|
CG
|
B:HIS8
|
4.0
|
12.5
|
1.0
|
ND1
|
B:HIS8
|
4.0
|
12.5
|
1.0
|
N
|
B:CYS38
|
4.1
|
10.8
|
1.0
|
CD2
|
B:HIS12
|
4.2
|
10.1
|
1.0
|
CA
|
B:HIS12
|
4.2
|
10.1
|
1.0
|
CA
|
B:CYS38
|
4.3
|
10.8
|
1.0
|
O
|
B:HIS8
|
4.5
|
12.5
|
1.0
|
CA
|
B:CYS35
|
4.6
|
23.5
|
1.0
|
CB
|
B:ALA37
|
5.0
|
10.8
|
1.0
|
|
Reference:
M.S.Barski,
T.Vanzo,
X.Zhao,
S.J.Smith,
A.Ballandras-Colas,
N.B.Cronin,
V.E.Pye,
S.H.Hughes,
T.R.Burke,
P.Cherepanov,
G.N.Maertens.
Structural Basis For the Inhibition of Htlv-1 Integration Inferred From Cryo-Em Deltaretroviral Intasome Structures Nat Commun 2021.
ISSN: ESSN 2041-1723
Page generated: Sun Aug 22 09:53:07 2021
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