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Zinc in PDB 7hzn: Group Deposition of Coxsackievirus A16 (G-10) 2A Protease in Complex with Inhibitors From the Asap Avidd Centre -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Asap-0018764- 002 (A71EV2A-X2448)

Enzymatic activity of Group Deposition of Coxsackievirus A16 (G-10) 2A Protease in Complex with Inhibitors From the Asap Avidd Centre -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Asap-0018764- 002 (A71EV2A-X2448)

All present enzymatic activity of Group Deposition of Coxsackievirus A16 (G-10) 2A Protease in Complex with Inhibitors From the Asap Avidd Centre -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Asap-0018764- 002 (A71EV2A-X2448):
3.4.22.29;

Protein crystallography data

The structure of Group Deposition of Coxsackievirus A16 (G-10) 2A Protease in Complex with Inhibitors From the Asap Avidd Centre -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Asap-0018764- 002 (A71EV2A-X2448), PDB code: 7hzn was solved by R.M.Lithgo, M.Fairhead, L.Koekemoer, B.H.Balcomb, E.Capkin, A.V.Chandran, M.Golding, A.S.Godoy, J.C.Aschenbrenner, P.G.Marples, X.Ni, W.Thompson, C.W.E.Tomlinson, C.Wild, M.Winokan, M.-A.E.Xavier, N.Kenton, J.Tucker, M.Dipoto, A.Lee, D.Fearon, F.Von Delft, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 47.45 / 1.33
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 86.973, 56.731, 32.645, 90, 95.46, 90
R / Rfree (%) 18.3 / 19.8

Zinc Binding Sites:

The binding sites of Zinc atom in the Group Deposition of Coxsackievirus A16 (G-10) 2A Protease in Complex with Inhibitors From the Asap Avidd Centre -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Asap-0018764- 002 (A71EV2A-X2448) (pdb code 7hzn). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Group Deposition of Coxsackievirus A16 (G-10) 2A Protease in Complex with Inhibitors From the Asap Avidd Centre -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Asap-0018764- 002 (A71EV2A-X2448), PDB code: 7hzn:

Zinc binding site 1 out of 1 in 7hzn

Go back to Zinc Binding Sites List in 7hzn
Zinc binding site 1 out of 1 in the Group Deposition of Coxsackievirus A16 (G-10) 2A Protease in Complex with Inhibitors From the Asap Avidd Centre -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Asap-0018764- 002 (A71EV2A-X2448)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Group Deposition of Coxsackievirus A16 (G-10) 2A Protease in Complex with Inhibitors From the Asap Avidd Centre -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Asap-0018764- 002 (A71EV2A-X2448) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn201

b:12.2
occ:1.00
ND1 A:HIS118 2.0 12.0 1.0
SG A:CYS116 2.3 11.7 1.0
SG A:CYS58 2.3 13.4 1.0
SG A:CYS56 2.3 11.8 1.0
CE1 A:HIS118 3.0 14.4 1.0
CG A:HIS118 3.0 13.1 1.0
CB A:CYS56 3.2 12.2 1.0
CB A:CYS58 3.2 13.1 1.0
CB A:CYS116 3.4 12.8 1.0
CB A:HIS118 3.4 12.9 1.0
N A:HIS118 3.9 14.3 1.0
NE2 A:HIS118 4.1 14.1 1.0
CD2 A:HIS118 4.2 12.8 1.0
N A:CYS58 4.2 12.1 1.0
CA A:CYS58 4.3 11.2 1.0
CA A:HIS118 4.4 13.2 1.0
N A:GLN117 4.5 14.2 1.0
CB A:ALA54 4.5 12.3 1.0
CG A:GLN117 4.5 18.4 1.0
CA A:CYS116 4.7 12.2 1.0
CA A:CYS56 4.7 11.5 1.0
O A:HOH481 4.8 21.5 1.0
C A:CYS116 4.8 12.2 1.0
C A:GLN117 4.9 14.8 1.0

Reference:

R.M.Lithgo, M.Fairhead, L.Koekemoer, B.H.Balcomb, E.Capkin, A.V.Chandran, M.Golding, A.S.Godoy, J.C.Aschenbrenner, P.G.Marples, X.Ni, W.Thompson, C.W.E.Tomlinson, C.Wild, M.Winokan, M.-A.E.Xavier, N.Kenton, J.Tucker, M.Dipoto, A.Lee, D.Fearon, F.Von Delft. Group Deposition of Coxsackievirus A16 (G-10) 2A Protease in Complex with Inhibitors From the Asap Avidd Centre To Be Published.
Page generated: Tue Feb 25 12:07:53 2025

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