Zinc in PDB 8zxc: uc(Nmr) Solution Structures of ASH1L Brd-Phd Domain in Complex with H3K4ME2 Peptide

The binding sites of Zinc atom in the uc(Nmr) Solution Structures of ASH1L Brd-Phd Domain in Complex with H3K4ME2 Peptide (pdb code 8zxc). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the uc(Nmr) Solution Structures of ASH1L Brd-Phd Domain in Complex with H3K4ME2 Peptide, PDB code: 8zxc:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the uc(Nmr) Solution Structures of ASH1L Brd-Phd Domain in Complex with H3K4ME2 Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of uc(Nmr) Solution Structures of ASH1L Brd-Phd Domain in Complex with H3K4ME2 Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn501 b:0.0 occ:1.00 ND1 A:HIS177 2.1 0.0 1.0 SG A:CYS155 2.3 0.0 1.0 SG A:CYS180 2.3 0.0 1.0 SG A:CYS157 2.3 0.0 1.0 HB2 A:HIS177 2.6 0.0 1.0 CE1 A:HIS177 3.1 0.0 1.0 CG A:HIS177 3.1 0.0 1.0 HB2 A:CYS157 3.1 0.0 1.0 HE1 A:HIS177 3.3 0.0 1.0 HB3 A:CYS155 3.3 0.0 1.0 CB A:CYS180 3.3 0.0 1.0 CB A:HIS177 3.4 0.0 1.0 CB A:CYS157 3.4 0.0 1.0 CB A:CYS155 3.4 0.0 1.0 HB2 A:CYS180 3.4 0.0 1.0 H A:CYS157 3.4 0.0 1.0 HB3 A:CYS180 3.5 0.0 1.0 HB2 A:CYS155 3.7 0.0 1.0 H A:HIS177 3.7 0.0 1.0 HG12 A:ILE156 4.0 0.0 1.0 HB3 A:HIS177 4.0 0.0 1.0 HB3 A:CYS157 4.2 0.0 1.0 N A:CYS157 4.2 0.0 1.0 NE2 A:HIS177 4.2 0.0 1.0 CD2 A:HIS177 4.2 0.0 1.0 CA A:CYS157 4.3 0.0 1.0 HD12 A:LEU159 4.4 0.0 1.0 N A:HIS177 4.4 0.0 1.0 CA A:HIS177 4.4 0.0 1.0 H A:ILE156 4.6 0.0 1.0 H A:CYS180 4.6 0.0 1.0 HA A:CYS157 4.6 0.0 1.0 CA A:CYS155 4.8 0.0 1.0 CA A:CYS180 4.8 0.0 1.0 O A:HIS177 4.9 0.0 1.0 N A:ILE156 4.9 0.0 1.0 CG1 A:ILE156 5.0 0.0 1.0

Zinc binding site 2 out of 2 in the uc(Nmr) Solution Structures of ASH1L Brd-Phd Domain in Complex with H3K4ME2 Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of uc(Nmr) Solution Structures of ASH1L Brd-Phd Domain in Complex with H3K4ME2 Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn502 b:0.0 occ:1.00 SG A:CYS172 2.3 0.0 1.0 SG A:CYS195 2.3 0.0 1.0 SG A:CYS192 2.3 0.0 1.0 SG A:CYS169 2.3 0.0 1.0 H A:CYS172 3.0 0.0 1.0 HB2 A:CYS195 3.1 0.0 1.0 HB3 A:CYS192 3.2 0.0 1.0 H A:CYS192 3.2 0.0 1.0 HB2 A:CYS172 3.2 0.0 1.0 HB2 A:LYS171 3.3 0.0 1.0 H A:CYS195 3.3 0.0 1.0 CB A:CYS172 3.3 0.0 1.0 CB A:CYS195 3.4 0.0 1.0 CB A:CYS192 3.4 0.0 1.0 CB A:CYS169 3.6 0.0 1.0 N A:CYS172 3.6 0.0 1.0 OE1 A:GLN194 3.6 0.0 1.0 HB2 A:CYS169 3.7 0.0 1.0 HB3 A:CYS169 3.7 0.0 1.0 HD23 A:LEU191 3.9 0.0 1.0 HB3 A:GLN194 4.0 0.0 1.0 N A:CYS192 4.0 0.0 1.0 CA A:CYS172 4.0 0.0 1.0 N A:CYS195 4.1 0.0 1.0 HG22 A:VAL174 4.1 0.0 1.0 HB3 A:CYS195 4.2 0.0 1.0 HB2 A:CYS192 4.2 0.0 1.0 HB3 A:CYS172 4.2 0.0 1.0 H A:LYS171 4.3 0.0 1.0 CA A:CYS192 4.3 0.0 1.0 CA A:CYS195 4.3 0.0 1.0 CB A:LYS171 4.3 0.0 1.0 CD A:GLN194 4.4 0.0 1.0 HA A:CYS172 4.4 0.0 1.0 C A:LYS171 4.6 0.0 1.0 HA A:LEU191 4.7 0.0 1.0 HG3 A:LYS171 4.7 0.0 1.0 HA A:CYS195 4.7 0.0 1.0 HE22 A:GLN194 4.8 0.0 1.0 HG23 A:VAL174 4.8 0.0 1.0 H A:GLN194 4.8 0.0 1.0 HB3 A:LYS171 4.8 0.0 1.0 CA A:LYS171 4.8 0.0 1.0 CD2 A:LEU191 4.9 0.0 1.0 HB3 A:LEU191 4.9 0.0 1.0 N A:LYS171 4.9 0.0 1.0 NE2 A:GLN194 4.9 0.0 1.0 CG2 A:VAL174 5.0 0.0 1.0 CA A:CYS169 5.0 0.0 1.0 C A:CYS192 5.0 0.0 1.0 CB A:GLN194 5.0 0.0 1.0

L.Zeng, M.-M.Zhou. uc(Nmr) Solution Structures of ASH1L Brd-Phd Domain in Complex with H3K4ME2 Peptide To Be Published.