Atomistry » Zinc » PDB 7gqu-7h48 » 7h43
Atomistry »
  Zinc »
    PDB 7gqu-7h48 »
      7h43 »

Zinc in PDB 7h43: Group Deposition For Crystallographic Fragment Screening of Coxsackievirus A16 (G-10) 2A Protease -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Z1246465616 (A71EV2A-X0541)

Enzymatic activity of Group Deposition For Crystallographic Fragment Screening of Coxsackievirus A16 (G-10) 2A Protease -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Z1246465616 (A71EV2A-X0541)

All present enzymatic activity of Group Deposition For Crystallographic Fragment Screening of Coxsackievirus A16 (G-10) 2A Protease -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Z1246465616 (A71EV2A-X0541):
3.4.22.29;

Protein crystallography data

The structure of Group Deposition For Crystallographic Fragment Screening of Coxsackievirus A16 (G-10) 2A Protease -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Z1246465616 (A71EV2A-X0541), PDB code: 7h43 was solved by R.M.Lithgo, M.Fairhead, L.Koekemoer, B.H.Balcomb, E.Capkin, A.V.Chandran, M.Golding, A.S.Godoy, J.C.Aschenbrenner, P.G.Marples, X.Ni, W.Thompson, C.W.E.Tomlinson, C.Wild, M.Winokan, M.-A.E.Xavier, D.Fearon, F.Von Delft, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 47.15 / 1.13
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 86.473, 56.354, 32.466, 90, 95.41, 90
R / Rfree (%) 19.7 / 20.5

Zinc Binding Sites:

The binding sites of Zinc atom in the Group Deposition For Crystallographic Fragment Screening of Coxsackievirus A16 (G-10) 2A Protease -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Z1246465616 (A71EV2A-X0541) (pdb code 7h43). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Group Deposition For Crystallographic Fragment Screening of Coxsackievirus A16 (G-10) 2A Protease -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Z1246465616 (A71EV2A-X0541), PDB code: 7h43:

Zinc binding site 1 out of 1 in 7h43

Go back to Zinc Binding Sites List in 7h43
Zinc binding site 1 out of 1 in the Group Deposition For Crystallographic Fragment Screening of Coxsackievirus A16 (G-10) 2A Protease -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Z1246465616 (A71EV2A-X0541)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Group Deposition For Crystallographic Fragment Screening of Coxsackievirus A16 (G-10) 2A Protease -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Z1246465616 (A71EV2A-X0541) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn202

b:11.3
occ:1.00
 ND1 A:HIS118 2.0 12.1 1.0
SG A:CYS116 2.3 11.3 1.0
SG A:CYS58 2.3 12.6 1.0
SG A:CYS56 2.3 11.1 1.0
CE1 A:HIS118 3.0 13.9 1.0
CG A:HIS118 3.1 12.6 1.0
CB A:CYS58 3.2 12.2 1.0
CB A:CYS56 3.2 9.6 1.0
CB A:CYS116 3.3 10.2 1.0
CB A:HIS118 3.5 13.2 1.0
N A:HIS118 3.9 13.8 1.0
NE2 A:HIS118 4.1 15.3 1.0
N A:CYS58 4.2 11.6 1.0
CD2 A:HIS118 4.2 13.4 1.0
CA A:CYS58 4.3 11.3 1.0
CA A:HIS118 4.3 13.2 1.0
CG A:GLN117 4.4 17.8 1.0
CB A:ALA54 4.5 11.2 1.0
N A:GLN117 4.5 13.5 1.0
CA A:CYS116 4.6 11.4 1.0
CA A:CYS56 4.6 9.9 1.0
O A:HOH479 4.7 20.9 1.0
C A:CYS116 4.8 10.7 1.0
C A:GLN117 4.9 14.2 1.0

Reference:

R.M.Lithgo, M.Fairhead, L.Koekemoer, B.H.Balcomb, E.Capkin, A.V.Chandran, M.Golding, A.S.Godoy, J.C.Aschenbrenner, P.G.Marples, X.Ni, W.Thompson, C.W.E.Tomlinson, C.Wild, M.Winokan, M.-A.E.Xavier, D.Fearon, F.Von Delft. Group Deposition For Crystallographic Fragment Screening of Coxsackievirus A16 (G-10) 2A Protease To Be Published.
Page generated: Tue Oct 29 20:48:33 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy