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Atomistry » Zinc » PDB 7gqu-7h48 » 7gqu » |
Zinc in PDB 7gqu: Crystal Structure of Werner Helicase Fragment 517-945 in Covalent Complex with N-[(E,1S)-1-Cyclopropyl-3-Methylsulfonylprop-2-Enyl]-2- (1,1-Difluoroethyl)-4-Phenoxypyrimidine-5-CarboxamideProtein crystallography data
The structure of Crystal Structure of Werner Helicase Fragment 517-945 in Covalent Complex with N-[(E,1S)-1-Cyclopropyl-3-Methylsulfonylprop-2-Enyl]-2- (1,1-Difluoroethyl)-4-Phenoxypyrimidine-5-Carboxamide, PDB code: 7gqu
was solved by
M.Classen,
J.Benz,
D.Brugger,
O.Tagliente,
M.G.Rudolph,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7gqu:
The structure of Crystal Structure of Werner Helicase Fragment 517-945 in Covalent Complex with N-[(E,1S)-1-Cyclopropyl-3-Methylsulfonylprop-2-Enyl]-2- (1,1-Difluoroethyl)-4-Phenoxypyrimidine-5-Carboxamide also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Werner Helicase Fragment 517-945 in Covalent Complex with N-[(E,1S)-1-Cyclopropyl-3-Methylsulfonylprop-2-Enyl]-2- (1,1-Difluoroethyl)-4-Phenoxypyrimidine-5-Carboxamide
(pdb code 7gqu). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Werner Helicase Fragment 517-945 in Covalent Complex with N-[(E,1S)-1-Cyclopropyl-3-Methylsulfonylprop-2-Enyl]-2- (1,1-Difluoroethyl)-4-Phenoxypyrimidine-5-Carboxamide, PDB code: 7gqu: Zinc binding site 1 out of 1 in 7gquGo back to Zinc Binding Sites List in 7gqu
Zinc binding site 1 out
of 1 in the Crystal Structure of Werner Helicase Fragment 517-945 in Covalent Complex with N-[(E,1S)-1-Cyclopropyl-3-Methylsulfonylprop-2-Enyl]-2- (1,1-Difluoroethyl)-4-Phenoxypyrimidine-5-Carboxamide
Mono view Stereo pair view
Reference:
K.A.Baltgalvis,
K.N.Lamb,
K.T.Symons,
C.C.Wu,
M.A.Hoffman,
A.N.Snead,
X.Song,
T.Glaza,
S.Kikuchi,
J.C.Green,
D.C.Rogness,
B.Lam,
M.E.Rodriguez-Aguirre,
D.R.Woody,
C.L.Eissler,
S.Rodiles,
S.M.Negron,
S.M.Bernard,
E.Tran,
J.Pollock,
A.Tabatabaei,
V.Contreras,
H.N.Williams,
M.K.Pastuszka,
J.J.Sigler,
P.Pettazzoni,
M.G.Rudolph,
M.Classen,
D.Brugger,
C.Claiborne,
J.M.Plancher,
I.Cuartas,
J.Seoane,
L.E.Burgess,
R.T.Abraham,
D.S.Weinstein,
G.M.Simon,
M.P.Patricelli,
T.M.Kinsella.
Chemoproteomic Discovery of A Covalent Allosteric Inhibitor of Wrn Helicase Nature 2024.
Page generated: Tue Oct 29 20:43:38 2024
ISSN: ESSN 1476-4687 DOI: 10.1038/S41586-024-07318-Y |
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