Zinc in PDB 7d0r: Crystal Structure of Human HBO1-BRPF2 in Complex with Crotonoyl- Coenzyme A

All present enzymatic activity of Crystal Structure of Human HBO1-BRPF2 in Complex with Crotonoyl- Coenzyme A:
2.3.1.48;

The structure of Crystal Structure of Human HBO1-BRPF2 in Complex with Crotonoyl- Coenzyme A, PDB code: 7d0r was solved by W.Li, J.Ding, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.01 / 1.95
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	127.345, 39.636, 88.096, 90, 123.24, 90
R / Rfree (%)	18.2 / 23.1

The binding sites of Zinc atom in the Crystal Structure of Human HBO1-BRPF2 in Complex with Crotonoyl- Coenzyme A (pdb code 7d0r). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human HBO1-BRPF2 in Complex with Crotonoyl- Coenzyme A, PDB code: 7d0r:

Zinc binding site 1 out of 1 in the Crystal Structure of Human HBO1-BRPF2 in Complex with Crotonoyl- Coenzyme A


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human HBO1-BRPF2 in Complex with Crotonoyl- Coenzyme A within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn702 b:41.6 occ:1.00 SG A:CYS371 2.3 39.8 1.0 SG A:CYS368 2.3 38.2 1.0 SG A:CYS388 2.3 43.8 1.0 NE2 A:HIS384 2.4 44.7 1.0 CB A:CYS368 3.1 39.5 1.0 CB A:CYS388 3.2 47.5 1.0 CB A:CYS371 3.2 36.3 1.0 CD2 A:HIS384 3.2 43.5 1.0 CE1 A:HIS384 3.5 43.7 1.0 N A:CYS371 3.8 34.6 1.0 O A:HOH886 3.9 75.6 1.0 CA A:CYS371 4.1 34.7 1.0 CG A:HIS384 4.4 44.1 1.0 ND1 A:HIS384 4.5 42.3 1.0 CA A:CYS368 4.5 40.2 1.0 CA A:CYS388 4.6 46.9 1.0 C A:CYS371 4.8 34.6 1.0 SD A:MET385 5.0 50.6 1.0 C A:PHE370 5.0 33.8 1.0 N A:LEU372 5.0 32.8 1.0

Y.Xiao, W.Li, L.Pan, H.Yang, L.Zhang, J.Chen, W.Wei, L.Lu, J.Ye, J.Li, G.Li, Y.Zhang, M.Tan, J.Ding, J.Wong. HBO1 Is A Versatile Histone Acyltransferase Critical For Promoter Histone Acylations To Be Published.