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Zinc in PDB 7b4a: Structural Basis of Reactivation of Oncogenic P53 Mutants By A Small Molecule: Methylene Quinuclidinone (Mq). Human P53DBD-R273H Mutant Bound to Dna: R273H-DnaProtein crystallography data
The structure of Structural Basis of Reactivation of Oncogenic P53 Mutants By A Small Molecule: Methylene Quinuclidinone (Mq). Human P53DBD-R273H Mutant Bound to Dna: R273H-Dna, PDB code: 7b4a
was solved by
D.Golovenko,
H.Rozenberg,
O.Degtjarik,
Z.Shakked,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Structural Basis of Reactivation of Oncogenic P53 Mutants By A Small Molecule: Methylene Quinuclidinone (Mq). Human P53DBD-R273H Mutant Bound to Dna: R273H-Dna
(pdb code 7b4a). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structural Basis of Reactivation of Oncogenic P53 Mutants By A Small Molecule: Methylene Quinuclidinone (Mq). Human P53DBD-R273H Mutant Bound to Dna: R273H-Dna, PDB code: 7b4a: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 7b4aGo back to Zinc Binding Sites List in 7b4a
Zinc binding site 1 out
of 2 in the Structural Basis of Reactivation of Oncogenic P53 Mutants By A Small Molecule: Methylene Quinuclidinone (Mq). Human P53DBD-R273H Mutant Bound to Dna: R273H-Dna
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 7b4aGo back to Zinc Binding Sites List in 7b4a
Zinc binding site 2 out
of 2 in the Structural Basis of Reactivation of Oncogenic P53 Mutants By A Small Molecule: Methylene Quinuclidinone (Mq). Human P53DBD-R273H Mutant Bound to Dna: R273H-Dna
Mono view Stereo pair view
Reference:
O.Degtjarik,
D.Golovenko,
Y.Diskin-Posner,
L.Abrahmsen,
H.Rozenberg,
Z.Shakked.
P53 Structure 4 To Be Published.
Page generated: Fri Dec 17 11:45:57 2021
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