Zinc in PDB 7af1: The Structure of Artemis/SNM1C/DCLRE1C with 2 Zinc Ions

The structure of The Structure of Artemis/SNM1C/DCLRE1C with 2 Zinc Ions, PDB code: 7af1 was solved by Y.Yosaatmadja, S.Goubin, J.A.Newman, S.M.M.Mukhopadhyay, A.A.Dannerfjord, N.A.Burgess-Brown, F.Von Delft, C.H.Arrowsmith, C.Bountra, O.Gileadi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.53 / 1.70
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	35.752, 47.973, 48.153, 82.68, 76.35, 85.81
R / Rfree (%)	19.1 / 21.2

The binding sites of Zinc atom in the The Structure of Artemis/SNM1C/DCLRE1C with 2 Zinc Ions (pdb code 7af1). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the The Structure of Artemis/SNM1C/DCLRE1C with 2 Zinc Ions, PDB code: 7af1:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the The Structure of Artemis/SNM1C/DCLRE1C with 2 Zinc Ions


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The Structure of Artemis/SNM1C/DCLRE1C with 2 Zinc Ions within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn402 b:15.7 occ:1.00 O A:HOH510 1.9 16.8 1.0 ND1 A:HIS35 2.2 15.2 1.0 NE2 A:HIS115 2.2 13.8 1.0 NE2 A:HIS33 2.2 12.4 1.0 O A:HOH614 2.3 22.6 1.0 OD2 A:ASP136 2.3 13.6 1.0 CE1 A:HIS35 3.0 15.2 1.0 CD2 A:HIS115 3.1 13.4 1.0 CD2 A:HIS33 3.1 12.3 1.0 CE1 A:HIS115 3.1 13.7 1.0 CG A:HIS35 3.2 14.7 1.0 ZN A:ZN404 3.2 14.9 0.3 CE1 A:HIS33 3.2 12.4 1.0 CG A:ASP136 3.4 12.9 1.0 CB A:HIS35 3.5 14.4 1.0 CB A:ASP136 3.8 12.1 1.0 CD2 A:HIS38 4.1 16.9 1.0 NE2 A:HIS38 4.1 17.6 1.0 NE2 A:HIS35 4.2 15.3 1.0 ND1 A:HIS115 4.2 13.5 1.0 CG A:HIS115 4.2 13.4 1.0 CD2 A:HIS35 4.3 15.8 1.0 CG A:HIS33 4.3 11.7 1.0 ND1 A:HIS33 4.3 12.2 1.0 OD1 A:ASP37 4.3 29.0 1.0 O A:HOH634 4.5 35.8 1.0 OD1 A:ASP136 4.5 13.1 1.0 OD2 A:ASP37 4.7 29.4 1.0 CE1 A:HIS319 4.9 12.9 1.0 CG A:ASP37 5.0 24.9 1.0

Zinc binding site 2 out of 3 in the The Structure of Artemis/SNM1C/DCLRE1C with 2 Zinc Ions


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of The Structure of Artemis/SNM1C/DCLRE1C with 2 Zinc Ions within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn403 b:13.2 occ:1.00 ND1 A:HIS254 2.1 12.8 1.0 ND1 A:HIS228 2.2 16.6 1.0 SG A:CYS272 2.3 14.3 1.0 SG A:CYS256 2.3 15.4 1.0 CE1 A:HIS254 3.0 12.9 1.0 CE1 A:HIS228 3.0 17.5 1.0 CB A:CYS272 3.1 15.3 1.0 CG A:HIS254 3.2 12.2 1.0 CG A:HIS228 3.3 16.9 1.0 CB A:CYS256 3.3 16.2 1.0 CB A:HIS254 3.6 12.3 1.0 CB A:HIS228 3.7 16.8 1.0 NE2 A:HIS254 4.1 12.8 1.0 N A:CYS272 4.2 16.8 1.0 NE2 A:HIS228 4.2 17.1 1.0 CD2 A:HIS254 4.3 12.6 1.0 CA A:CYS272 4.3 16.0 1.0 CD2 A:HIS228 4.3 17.2 1.0 N A:CYS256 4.6 16.0 1.0 CA A:CYS256 4.6 16.9 1.0 CA A:HIS254 4.6 12.9 1.0 CB A:LEU270 4.7 23.9 1.0 CD1 A:LEU270 4.9 24.1 1.0

Zinc binding site 3 out of 3 in the The Structure of Artemis/SNM1C/DCLRE1C with 2 Zinc Ions


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of The Structure of Artemis/SNM1C/DCLRE1C with 2 Zinc Ions within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn404 b:14.9 occ:0.30 O A:HOH510 2.1 16.8 1.0 OD2 A:ASP136 2.1 13.6 1.0 O A:HOH506 2.2 28.0 1.0 OD2 A:ASP37 2.2 29.4 1.0 NE2 A:HIS38 2.5 17.6 1.0 CG A:ASP136 3.0 12.9 1.0 CD2 A:HIS38 3.0 16.9 1.0 O A:HOH614 3.1 22.6 1.0 CG A:ASP37 3.2 24.9 1.0 OD1 A:ASP136 3.2 13.1 1.0 O A:HOH634 3.2 35.8 1.0 ZN A:ZN402 3.2 15.7 1.0 OD1 A:ASP37 3.4 29.0 1.0 CE1 A:HIS38 3.7 17.2 1.0 O A:HOH566 4.1 28.9 1.0 CG A:HIS38 4.3 16.1 1.0 NE2 A:HIS33 4.4 12.4 1.0 CB A:ASP136 4.4 12.1 1.0 CE1 A:HIS319 4.5 12.9 1.0 CB A:ASP37 4.6 21.7 1.0 ND1 A:HIS38 4.6 17.2 1.0 CE1 A:HIS33 4.6 12.4 1.0 NE2 A:HIS115 4.8 13.8 1.0 ND1 A:HIS35 4.9 15.2 1.0

Y.Yosaatmadja, S.Goubin, J.A.Newman, S.M.M.Mukhopadhyay, A.A.Dannerfjord, N.A.Burgess-Brown, F.Von Delft, C.H.Arrowsmith, C.Bountra, O.Gileadi. The Structure of Artemis/SNM1C/DCLRE1C with 2 Zinc Ions To Be Published.