Zinc in PDB 6yze: Zinc Metalloprotease Proa From Native Source

The structure of Zinc Metalloprotease Proa From Native Source, PDB code: 6yze was solved by S.Schmelz, W.Blankenfeldt, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.90 / 2.18
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	40.633, 54.604, 134.519, 90, 90, 90
R / Rfree (%)	20.5 / 26.6

The binding sites of Zinc atom in the Zinc Metalloprotease Proa From Native Source (pdb code 6yze). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Zinc Metalloprotease Proa From Native Source, PDB code: 6yze:

Zinc binding site 1 out of 1 in the Zinc Metalloprotease Proa From Native Source


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Zinc Metalloprotease Proa From Native Source within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:30.9 occ:1.00 OE1 A:GLU194 1.9 21.5 1.0 NE2 A:HIS174 2.2 13.7 1.0 NE2 A:HIS170 2.2 17.5 1.0 CD A:GLU194 2.7 18.0 1.0 OE2 A:GLU194 2.9 19.2 1.0 CD2 A:HIS170 3.0 15.6 1.0 CE1 A:HIS174 3.2 16.5 1.0 CD2 A:HIS174 3.2 16.0 1.0 CE1 A:HIS170 3.3 20.9 1.0 OE2 A:GLU171 3.8 35.7 1.0 OH A:TYR185 3.9 18.5 1.0 CG A:GLU194 4.2 16.9 1.0 CG A:HIS170 4.2 24.4 1.0 NE2 A:HIS256 4.2 20.3 1.0 ND1 A:HIS174 4.3 15.7 1.0 ND1 A:HIS170 4.3 17.7 1.0 CG A:HIS174 4.3 17.1 1.0 CD A:GLU171 4.5 25.3 1.0 OE1 A:GLU171 4.5 23.9 1.0 CB A:SER197 4.6 20.4 1.0 OG A:SER197 4.7 19.8 1.0 CD2 A:HIS256 4.7 18.2 1.0 CZ A:TYR185 4.9 14.1 1.0 CA A:GLU194 4.9 25.6 1.0 CE1 A:TYR185 4.9 15.8 1.0

L.Scheithauer, S.Thiem, S.Schmelz, A.Dellmann, K.Bussow, R.M.H.J.Brouwer, C.M.Unal, W.Blankenfeldt, M.Steinert. Zinc Metalloprotease Proa of Legionella Pneumophila Increases Alveolar Septal Thickness in Human Lung Tissue Explants By Collagen IV Degradation. Cell.Microbiol. 13313 2021.
ISSN: ESSN 1462-5822
PubMed: 33491325
DOI: 10.1111/CMI.13313