Zinc in PDB 6wbj: High Resolution Crystal Structure of Mreck(CC4) in Fusion with Engineered Mbp

The structure of High Resolution Crystal Structure of Mreck(CC4) in Fusion with Engineered Mbp, PDB code: 6wbj was solved by T.H.Chang, F.L.Hsieh, S.B.Gabelli, J.Nathans, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	57.82 / 1.65
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	80.404, 110.221, 57.816, 90.00, 90.00, 90.00
R / Rfree (%)	15.6 / 17.7

The binding sites of Zinc atom in the High Resolution Crystal Structure of Mreck(CC4) in Fusion with Engineered Mbp (pdb code 6wbj). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the High Resolution Crystal Structure of Mreck(CC4) in Fusion with Engineered Mbp, PDB code: 6wbj:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the High Resolution Crystal Structure of Mreck(CC4) in Fusion with Engineered Mbp


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of High Resolution Crystal Structure of Mreck(CC4) in Fusion with Engineered Mbp within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn503 b:11.7 occ:0.57 OE1 A:GLU223 1.9 24.4 1.0 NE2 A:HIS217 2.0 18.3 1.0 CD A:GLU223 2.7 19.6 1.0 OE2 A:GLU223 2.8 18.7 1.0 CD2 A:HIS217 2.9 16.5 1.0 CE1 A:HIS217 3.0 18.4 1.0 HD2 A:HIS217 3.1 19.8 1.0 HE1 A:HIS217 3.3 22.1 1.0 O A:HOH1016 3.8 36.1 1.0 HB2 A:HIS221 4.1 21.1 1.0 CG A:HIS217 4.1 15.2 1.0 ND1 A:HIS217 4.1 18.2 1.0 CG A:GLU223 4.2 17.2 1.0 O A:HOH812 4.2 37.6 1.0 HB3 A:HIS221 4.3 21.1 1.0 HG2 A:GLU223 4.4 20.6 1.0 HG3 A:GLU223 4.5 20.6 1.0 CB A:HIS221 4.6 17.6 1.0 HA A:ALA218 4.7 18.1 1.0 CG A:HIS221 4.8 21.6 1.0 HD1 A:HIS217 4.9 21.9 1.0

Zinc binding site 2 out of 2 in the High Resolution Crystal Structure of Mreck(CC4) in Fusion with Engineered Mbp


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of High Resolution Crystal Structure of Mreck(CC4) in Fusion with Engineered Mbp within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn504 b:90.8 occ:1.00 HD1 A:HIS217 2.5 21.9 1.0 HE1 A:HIS221 2.9 28.6 1.0 O A:HOH995 3.1 28.7 1.0 ND1 A:HIS217 3.3 18.2 1.0 O A:HOH1025 3.5 50.0 1.0 CE1 A:HIS221 3.6 23.8 1.0 O A:HOH1005 3.9 30.6 1.0 HB2 A:HIS217 3.9 15.9 1.0 HE1 A:HIS217 4.1 22.1 1.0 CE1 A:HIS217 4.1 18.4 1.0 NE2 A:HIS221 4.2 26.5 1.0 HA A:HIS217 4.3 17.3 1.0 CG A:HIS217 4.3 15.2 1.0 O A:HOH856 4.4 53.0 1.0 CB A:HIS217 4.5 13.3 1.0 O A:HOH864 4.5 29.9 1.0 ND1 A:HIS221 4.6 20.6 1.0 HD1 A:HIS221 4.7 24.7 1.0 CA A:HIS217 5.0 14.4 1.0

T.H.Chang, F.L.Hsieh, P.M.Smallwood, S.B.Gabelli, J.Nathans. Structure of the Reck Cc Domain, An Evolutionary Anomaly Proc.Natl.Acad.Sci.Usa 2020.
ISSN: ESSN 1091-6490