Zinc in PDB 6wbh: Crystal Structure of Mreck(CC4) in Fusion with Engineered Mbp at Medium Resolution

The structure of Crystal Structure of Mreck(CC4) in Fusion with Engineered Mbp at Medium Resolution, PDB code: 6wbh was solved by T.H.Chang, F.L.Hsieh, S.B.Gabelli, J.Nathans, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.53 / 2.46
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	80.222, 110.599, 57.791, 90.00, 90.00, 90.00
R / Rfree (%)	19.4 / 22

The structure of Crystal Structure of Mreck(CC4) in Fusion with Engineered Mbp at Medium Resolution also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

The binding sites of Zinc atom in the Crystal Structure of Mreck(CC4) in Fusion with Engineered Mbp at Medium Resolution (pdb code 6wbh). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Mreck(CC4) in Fusion with Engineered Mbp at Medium Resolution, PDB code: 6wbh:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Mreck(CC4) in Fusion with Engineered Mbp at Medium Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Mreck(CC4) in Fusion with Engineered Mbp at Medium Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn503 b:11.2 occ:0.72 OE2 A:GLU223 2.2 15.9 1.0 NE2 A:HIS217 2.3 16.5 1.0 CD A:GLU223 2.9 16.5 1.0 OE1 A:GLU223 3.1 14.8 1.0 CD2 A:HIS217 3.2 13.4 1.0 CE1 A:HIS217 3.2 15.1 1.0 HD2 A:HIS217 3.3 16.1 1.0 HE1 A:HIS217 3.4 18.2 1.0 O A:HOH724 3.8 31.2 1.0 O A:HOH657 3.9 29.4 1.0 HB2 A:HIS221 4.1 17.6 1.0 HB3 A:HIS221 4.3 17.6 1.0 ND1 A:HIS217 4.3 14.1 1.0 CG A:HIS217 4.3 13.1 1.0 CG A:GLU223 4.4 15.9 1.0 HG2 A:GLU223 4.6 19.1 1.0 CB A:HIS221 4.6 14.7 1.0 HG3 A:GLU223 4.7 19.1 1.0 HA A:ALA218 4.9 14.2 1.0 CG A:HIS221 5.0 15.0 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Mreck(CC4) in Fusion with Engineered Mbp at Medium Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Mreck(CC4) in Fusion with Engineered Mbp at Medium Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn504 b:82.4 occ:1.00 HD1 A:HIS217 2.8 16.9 1.0 O A:HOH789 3.5 29.1 1.0 NE2 A:HIS221 3.6 15.2 1.0 ND1 A:HIS217 3.7 14.1 1.0 HE1 A:HIS221 4.1 19.0 1.0 CE1 A:HIS221 4.2 15.8 1.0 HB2 A:HIS217 4.2 14.9 1.0 HE1 A:HIS217 4.3 18.2 1.0 CE1 A:HIS217 4.4 15.1 1.0 CD2 A:HIS221 4.5 15.0 1.0 HD2 A:HIS221 4.7 18.0 1.0 CG A:HIS217 4.7 13.1 1.0 HA A:HIS217 4.8 14.3 1.0 CB A:HIS217 4.9 12.4 1.0

T.H.Chang, F.L.Hsieh, P.M.Smallwood, S.B.Gabelli, J.Nathans. Structure of the Reck Cc Domain, An Evolutionary Anomaly Proc.Natl.Acad.Sci.Usa 2020.
ISSN: ESSN 1091-6490