Zinc in PDB 6w4h: 1.80 Angstrom Resolution Crystal Structure of NSP16 - NSP10 Complex From Sars-Cov-2

The structure of 1.80 Angstrom Resolution Crystal Structure of NSP16 - NSP10 Complex From Sars-Cov-2, PDB code: 6w4h was solved by G.Minasov, L.Shuvalova, M.Rosas-Lemus, O.Kiryukhina, G.Wiersum, A.Godzik, L.Jaroszewski, P.J.Stogios, T.Skarina, K.J.F.Satchell, Center Forstructural Genomics Of Infectious Diseases (Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.76 / 1.80
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	167.740, 167.740, 51.942, 90.00, 90.00, 120.00
R / Rfree (%)	14.9 / 16.3

The binding sites of Zinc atom in the 1.80 Angstrom Resolution Crystal Structure of NSP16 - NSP10 Complex From Sars-Cov-2 (pdb code 6w4h). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the 1.80 Angstrom Resolution Crystal Structure of NSP16 - NSP10 Complex From Sars-Cov-2, PDB code: 6w4h:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the 1.80 Angstrom Resolution Crystal Structure of NSP16 - NSP10 Complex From Sars-Cov-2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of 1.80 Angstrom Resolution Crystal Structure of NSP16 - NSP10 Complex From Sars-Cov-2 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn4401 b:32.3 occ:1.00 NE2 B:HIS4336 2.0 32.3 1.0 SG B:CYS4327 2.3 30.7 1.0 SG B:CYS4343 2.3 35.2 1.0 SG B:CYS4330 2.3 30.2 1.0 CE1 B:HIS4336 3.0 33.3 1.0 CD2 B:HIS4336 3.0 34.9 1.0 CB B:CYS4327 3.2 28.8 1.0 CB B:CYS4343 3.3 38.5 1.0 CB B:CYS4330 3.4 29.2 1.0 N B:CYS4330 3.6 30.1 1.0 CA B:CYS4330 4.0 29.5 1.0 ND1 B:HIS4336 4.1 35.3 1.0 CG B:HIS4336 4.1 36.4 1.0 O B:HOH4597 4.2 54.2 1.0 CA B:CYS4343 4.5 41.1 1.0 CB B:TYR4329 4.6 33.8 1.0 C B:TYR4329 4.6 30.9 1.0 CA B:CYS4327 4.6 28.3 1.0 CB B:LYS4346 4.8 35.0 1.0 CA B:TYR4329 4.9 31.9 1.0 N B:LYS4346 5.0 31.4 1.0

Zinc binding site 2 out of 2 in the 1.80 Angstrom Resolution Crystal Structure of NSP16 - NSP10 Complex From Sars-Cov-2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of 1.80 Angstrom Resolution Crystal Structure of NSP16 - NSP10 Complex From Sars-Cov-2 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn4402 b:55.5 occ:1.00 SG B:CYS4370 2.3 55.7 1.0 SG B:CYS4383 2.3 66.8 1.0 SG B:CYS4373 2.3 50.8 1.0 SG B:CYS4381 2.3 53.4 1.0 CB B:CYS4370 3.1 52.9 1.0 CB B:CYS4381 3.4 50.4 1.0 CB B:CYS4383 3.4 71.2 1.0 CB B:CYS4373 3.4 52.3 1.0 N B:CYS4373 3.8 55.3 1.0 O B:HOH4568 3.9 39.0 0.5 CA B:CYS4381 4.0 50.6 1.0 N B:CYS4383 4.1 67.6 1.0 O B:HOH4584 4.2 42.5 0.5 CA B:CYS4373 4.2 52.2 1.0 CA B:CYS4383 4.4 72.8 1.0 N B:SER4382 4.5 57.4 1.0 C B:CYS4381 4.5 54.4 1.0 CA B:CYS4370 4.6 52.9 1.0 CB B:VAL4372 4.6 65.0 1.0 C B:VAL4372 4.9 58.9 1.0

G.Minasov, L.Shuvalova, M.Rosas-Lemus, O.Kiryukhina, G.Wiersum, A.Godzik, L.Jaroszewski, P.J.Stogios, T.Skarina, K.J.F.Satchell. 1.80 Angstrom Resolution Crystal Structure of NSP16 - NSP10 Complex From Sars-Cov-2 To Be Published.