Zinc in PDB 6vvt: Crystal Structure of A Mycobacterium Smegmatis Transcription Initiation Complex with Rifampicin-Resistant Rna Polymerase and Antibiotic Sorangicin
Enzymatic activity of Crystal Structure of A Mycobacterium Smegmatis Transcription Initiation Complex with Rifampicin-Resistant Rna Polymerase and Antibiotic Sorangicin
All present enzymatic activity of Crystal Structure of A Mycobacterium Smegmatis Transcription Initiation Complex with Rifampicin-Resistant Rna Polymerase and Antibiotic Sorangicin:
2.7.7.6;
2.7.7.6;
Protein crystallography data
The structure of Crystal Structure of A Mycobacterium Smegmatis Transcription Initiation Complex with Rifampicin-Resistant Rna Polymerase and Antibiotic Sorangicin, PDB code: 6vvt
was solved by
M.Lilic,
S.A.Darst,
E.A.Campbell,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 49.75 / 2.90 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 129.217, 162.212, 136.295, 90.00, 111.36, 90.00 |
| R / Rfree (%) | 24 / 27.5 |
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of A Mycobacterium Smegmatis Transcription Initiation Complex with Rifampicin-Resistant Rna Polymerase and Antibiotic Sorangicin
(pdb code 6vvt). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of A Mycobacterium Smegmatis Transcription Initiation Complex with Rifampicin-Resistant Rna Polymerase and Antibiotic Sorangicin, PDB code: 6vvt:
Jump to Zinc binding site number: 1; 2;
In total 2 binding sites of Zinc where determined in the Crystal Structure of A Mycobacterium Smegmatis Transcription Initiation Complex with Rifampicin-Resistant Rna Polymerase and Antibiotic Sorangicin, PDB code: 6vvt:
Jump to Zinc binding site number: 1; 2;
Zinc binding site 1 out of 2 in 6vvt
Go back to
Zinc Binding Sites List in 6vvt
Zinc binding site 1 out
of 2 in the Crystal Structure of A Mycobacterium Smegmatis Transcription Initiation Complex with Rifampicin-Resistant Rna Polymerase and Antibiotic Sorangicin
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Crystal Structure of A Mycobacterium Smegmatis Transcription Initiation Complex with Rifampicin-Resistant Rna Polymerase and Antibiotic Sorangicin within 5.0Å range:
|
Zinc binding site 2 out of 2 in 6vvt
Go back to
Zinc Binding Sites List in 6vvt
Zinc binding site 2 out
of 2 in the Crystal Structure of A Mycobacterium Smegmatis Transcription Initiation Complex with Rifampicin-Resistant Rna Polymerase and Antibiotic Sorangicin
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Crystal Structure of A Mycobacterium Smegmatis Transcription Initiation Complex with Rifampicin-Resistant Rna Polymerase and Antibiotic Sorangicin within 5.0Å range:
|
Reference:
M.Lilic,
J.Chen,
H.Boyaci,
N.Braffman,
E.A.Hubin,
J.Herrmann,
R.Muller,
R.Mooney,
R.Landick,
S.A.Darst,
E.A.Campbell.
The Antibiotic Sorangicin A Inhibits Promoter Dna Unwinding in A Mycobacterium Tuberculosis Rifampicin-Resistant Rna Polymerase. Proc.Natl.Acad.Sci.Usa 2020.
ISSN: ESSN 1091-6490
PubMed: 33199626
DOI: 10.1073/PNAS.2013706117
Page generated: Wed Dec 16 13:02:42 2020
ISSN: ESSN 1091-6490
PubMed: 33199626
DOI: 10.1073/PNAS.2013706117
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