Zinc in PDB 6shx: Dna Mismatch Repair Proteins MLH1 and MLH3

The structure of Dna Mismatch Repair Proteins MLH1 and MLH3, PDB code: 6shx was solved by J.Dai, P.Chervy, P.Legrand, V.Ropars, J.B.Charbonnier, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	24.64 / 2.40
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	93.59, 104.05, 134.08, 90, 90, 90
R / Rfree (%)	21.3 / 23.6

The binding sites of Zinc atom in the Dna Mismatch Repair Proteins MLH1 and MLH3 (pdb code 6shx). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Dna Mismatch Repair Proteins MLH1 and MLH3, PDB code: 6shx:

Zinc binding site 1 out of 1 in the Dna Mismatch Repair Proteins MLH1 and MLH3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Dna Mismatch Repair Proteins MLH1 and MLH3 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn901 b:68.8 occ:1.00 OE1 B:GLU529 1.9 48.7 1.0 NE2 B:HIS525 2.2 38.5 1.0 SG B:CYS670 2.5 37.1 1.0 SG A:CYS769 2.5 78.8 1.0 CD B:GLU529 3.0 56.6 1.0 CD2 B:HIS525 3.2 38.1 1.0 CB B:CYS670 3.2 32.3 1.0 CE1 B:HIS525 3.3 38.6 1.0 OE2 B:GLU529 3.6 46.8 1.0 CB A:CYS769 3.6 76.2 1.0 CA B:CYS670 3.8 31.8 1.0 O A:HOH828 3.9 53.6 1.0 CE1 B:HIS703 4.0 52.5 1.0 ND1 B:HIS703 4.2 52.6 1.0 CG B:GLU529 4.3 42.6 1.0 CG B:HIS525 4.4 37.0 1.0 ND1 B:HIS525 4.4 39.2 1.0 O B:CYS670 4.4 36.9 1.0 C B:CYS670 4.5 37.2 1.0 CA A:CYS769 4.7 76.0 1.0 CB B:GLU529 4.9 33.0 1.0

J.Dai, P.Chervy, J.B.Charbonnier. Dna Mismatch Repair Proteins MLH1 and MLH3 To Be Published.