Zinc in PDB 6sho: Sad Structure of Human Survivin Recovered By Continuous Rotation Data Collection and Multivariate Analysis of Friedel Pairs

The structure of Sad Structure of Human Survivin Recovered By Continuous Rotation Data Collection and Multivariate Analysis of Friedel Pairs, PDB code: 6sho was solved by M.J.Garcia-Bonete, G.Katona, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.59 / 3.20
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	113.980, 71.020, 81.340, 90.00, 128.48, 90.00
R / Rfree (%)	20.1 / 25.9

The binding sites of Zinc atom in the Sad Structure of Human Survivin Recovered By Continuous Rotation Data Collection and Multivariate Analysis of Friedel Pairs (pdb code 6sho). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Sad Structure of Human Survivin Recovered By Continuous Rotation Data Collection and Multivariate Analysis of Friedel Pairs, PDB code: 6sho:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Sad Structure of Human Survivin Recovered By Continuous Rotation Data Collection and Multivariate Analysis of Friedel Pairs


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Sad Structure of Human Survivin Recovered By Continuous Rotation Data Collection and Multivariate Analysis of Friedel Pairs within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:80.5 occ:1.00 SG A:CYS57 2.1 0.9 1.0 NE2 A:HIS77 2.2 89.1 1.0 SG A:CYS60 2.4 74.5 1.0 CE1 A:HIS77 2.5 86.4 1.0 SG A:CYS84 2.5 76.0 1.0 CB A:CYS57 2.8 84.8 1.0 CB A:CYS84 3.5 80.3 1.0 CB A:CYS60 3.5 75.2 1.0 CD2 A:HIS77 3.5 91.5 1.0 N A:CYS60 3.7 79.3 1.0 ND1 A:HIS77 3.7 87.5 1.0 CA A:CYS60 4.2 77.8 1.0 CA A:CYS57 4.2 83.8 1.0 CG A:HIS77 4.3 90.4 1.0 CB A:PHE59 4.6 75.9 1.0 C A:CYS57 4.8 86.8 1.0 C A:PHE59 4.8 81.4 1.0 CA A:CYS84 4.8 89.4 1.0 N A:PHE61 4.8 73.1 1.0 OG A:SER81 4.9 87.2 1.0 C A:CYS60 4.9 75.4 1.0 N A:PHE59 4.9 75.2 1.0 CB A:PHE86 5.0 95.3 1.0

Zinc binding site 2 out of 2 in the Sad Structure of Human Survivin Recovered By Continuous Rotation Data Collection and Multivariate Analysis of Friedel Pairs


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Sad Structure of Human Survivin Recovered By Continuous Rotation Data Collection and Multivariate Analysis of Friedel Pairs within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn201 b:85.6 occ:1.00 SG B:CYS84 2.1 0.8 1.0 CE1 B:HIS77 2.2 0.1 1.0 SG B:CYS57 2.4 63.0 1.0 SG B:CYS60 2.4 87.6 1.0 NE2 B:HIS77 2.5 97.8 1.0 CB B:CYS84 2.7 0.3 1.0 CB B:CYS60 2.8 77.8 1.0 N B:CYS60 3.3 78.6 1.0 CB B:CYS57 3.4 75.0 1.0 ND1 B:HIS77 3.5 1.0 1.0 CA B:CYS60 3.6 74.8 1.0 CD2 B:HIS77 3.8 0.1 1.0 CA B:CYS84 4.0 0.7 1.0 CG B:HIS77 4.3 0.7 1.0 OG B:SER81 4.3 91.7 1.0 C B:PHE59 4.5 81.9 1.0 C B:CYS60 4.6 75.3 1.0 CB B:PHE59 4.6 82.0 1.0 N B:PHE61 4.7 76.2 1.0 CA B:CYS57 4.8 74.9 1.0 C B:CYS84 4.8 0.3 1.0 CB B:SER81 4.8 96.0 1.0 CB B:PHE86 4.9 85.5 1.0 CD1 B:PHE59 4.9 96.3 1.0 CA B:PHE59 4.9 77.2 1.0 N B:PHE59 5.0 77.0 1.0

M.J.Garcia-Bonete, G.Katona. Bayesian Machine Learning Improves Single-Wavelength Anomalous Diffraction Phasing. Acta Crystallogr.,Sect.A V. 75 851 2019.
ISSN: ESSN 2053-2733
PubMed: 31692460
DOI: 10.1107/S2053273319011446