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Atomistry » Zinc » PDB 6sd7-6siy » 6sds » |
Zinc in PDB 6sds: Human Carbonic Anhydrase II in Complex with A Sulfonamide InhibitorEnzymatic activity of Human Carbonic Anhydrase II in Complex with A Sulfonamide Inhibitor
All present enzymatic activity of Human Carbonic Anhydrase II in Complex with A Sulfonamide Inhibitor:
4.2.1.1; Protein crystallography data
The structure of Human Carbonic Anhydrase II in Complex with A Sulfonamide Inhibitor, PDB code: 6sds
was solved by
V.Alterio,
G.De Simone,
D.Esposito,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Human Carbonic Anhydrase II in Complex with A Sulfonamide Inhibitor
(pdb code 6sds). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Human Carbonic Anhydrase II in Complex with A Sulfonamide Inhibitor, PDB code: 6sds: Zinc binding site 1 out of 1 in 6sdsGo back to Zinc Binding Sites List in 6sds
Zinc binding site 1 out
of 1 in the Human Carbonic Anhydrase II in Complex with A Sulfonamide Inhibitor
Mono view Stereo pair view
Reference:
A.Nocentini,
V.Alterio,
S.Bua,
L.Micheli,
D.Esposito,
M.Buonanno,
G.Bartolucci,
S.M.Osman,
Z.A.Alothman,
R.Cirilli,
M.Pierini,
S.M.Monti,
L.Di Cesare Mannelli,
P.Gratteri,
C.Ghelardini,
G.De Simone,
C.T.Supuran.
Phenyl(Thio)Phosphon(Amid)Ate Benzenesulfonamides As Potent and Selective Inhibitors of Human Carbonic Anhydrases II and VII Counteract Allodynia in A Mouse Model of Oxaliplatin-Induced Neuropathy. J.Med.Chem. V. 63 5185 2020.
Page generated: Tue Oct 29 07:18:56 2024
ISSN: ISSN 0022-2623 PubMed: 32364386 DOI: 10.1021/ACS.JMEDCHEM.9B02135 |
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