Zinc in PDB 6ric: Structure of the Core Vaccinia Virus Dna-Dependent Rna Polymerase Complex

All present enzymatic activity of Structure of the Core Vaccinia Virus Dna-Dependent Rna Polymerase Complex:
2.7.7.6;

The structure of Structure of the Core Vaccinia Virus Dna-Dependent Rna Polymerase Complex also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Zinc atom in the Structure of the Core Vaccinia Virus Dna-Dependent Rna Polymerase Complex (pdb code 6ric). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Structure of the Core Vaccinia Virus Dna-Dependent Rna Polymerase Complex, PDB code: 6ric:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Structure of the Core Vaccinia Virus Dna-Dependent Rna Polymerase Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of the Core Vaccinia Virus Dna-Dependent Rna Polymerase Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1302 b:0.7 occ:1.00 NE2 A:HIS62 2.1 67.5 1.0 SG A:CYS59 2.2 71.0 1.0 SG A:CYS49 2.3 76.9 1.0 SG A:CYS52 2.3 76.2 1.0 CB A:CYS49 2.8 76.9 1.0 CD2 A:HIS62 2.9 67.5 1.0 CE1 A:HIS62 3.2 67.5 1.0 CB A:CYS59 3.5 71.0 1.0 CB A:CYS52 3.5 76.2 1.0 N A:CYS52 3.8 76.2 1.0 CG A:HIS62 4.1 67.5 1.0 CA A:GLY42 4.1 74.0 1.0 ND1 A:HIS62 4.2 67.5 1.0 CA A:CYS52 4.3 76.2 1.0 CA A:CYS49 4.3 76.9 1.0 CB A:THR51 4.6 73.7 1.0 C A:GLY42 4.6 74.0 1.0 N A:GLY42 4.7 74.0 1.0 N A:GLY53 4.7 74.3 1.0 CA A:CYS59 4.7 71.0 1.0 N A:ALA43 4.7 76.7 1.0 N A:THR51 4.8 73.7 1.0 C A:CYS49 4.8 76.9 1.0 C A:THR51 4.9 73.7 1.0 N A:GLY61 4.9 65.4 1.0 CA A:GLY61 4.9 65.4 1.0 CA A:THR51 5.0 73.7 1.0

Zinc binding site 2 out of 4 in the Structure of the Core Vaccinia Virus Dna-Dependent Rna Polymerase Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of the Core Vaccinia Virus Dna-Dependent Rna Polymerase Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1303 b:96.8 occ:1.00 SG A:CYS93 2.3 54.5 1.0 SG A:CYS130 2.3 75.1 1.0 SG A:CYS135 2.3 66.3 1.0 SG A:CYS90 2.3 59.0 1.0 CB A:CYS130 2.6 75.1 1.0 CB A:CYS90 3.1 59.0 1.0 CB A:CYS135 3.6 66.3 1.0 N A:CYS93 3.7 54.5 1.0 CB A:CYS93 3.7 54.5 1.0 O A:CYS135 3.8 66.3 1.0 OD1 A:ASN132 3.8 64.9 1.0 CA A:CYS130 4.1 75.1 1.0 C A:CYS135 4.2 66.3 1.0 CA A:CYS93 4.3 54.5 1.0 CA A:CYS135 4.5 66.3 1.0 CB A:HIS92 4.5 54.6 1.0 CA A:CYS90 4.6 59.0 1.0 C A:HIS92 4.7 54.6 1.0 N A:GLN137 4.8 69.6 1.0 N A:HIS92 4.8 54.6 1.0 N A:CYS130 4.8 75.1 1.0 O A:GLN137 4.8 69.6 1.0 CA A:HIS92 4.9 54.6 1.0 N A:MET136 4.9 72.2 1.0 C A:CYS130 5.0 75.1 1.0

Zinc binding site 3 out of 4 in the Structure of the Core Vaccinia Virus Dna-Dependent Rna Polymerase Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Structure of the Core Vaccinia Virus Dna-Dependent Rna Polymerase Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1201 b:0.1 occ:1.00 SG B:CYS1103 2.2 64.2 1.0 SG B:CYS1090 2.3 65.0 1.0 SG B:CYS1106 2.3 59.7 1.0 SG B:CYS1087 2.3 65.0 1.0 CB B:CYS1106 3.0 59.7 1.0 CB B:CYS1103 3.0 64.2 1.0 CB B:CYS1087 3.0 65.0 1.0 CB B:PRO1113 3.8 57.2 1.0 N B:CYS1106 3.9 59.7 1.0 CB B:CYS1090 3.9 65.0 1.0 CG B:PRO1113 4.0 57.2 1.0 CA B:CYS1106 4.1 59.7 1.0 N B:CYS1090 4.1 65.0 1.0 CA B:CYS1087 4.4 65.0 1.0 CA B:CYS1103 4.5 64.2 1.0 CA B:CYS1090 4.5 65.0 1.0 OD1 B:ASP1092 4.6 62.3 1.0 O B:CYS1090 4.9 65.0 1.0 CB B:ASN1089 4.9 64.9 1.0 C B:CYS1090 5.0 65.0 1.0

Zinc binding site 4 out of 4 in the Structure of the Core Vaccinia Virus Dna-Dependent Rna Polymerase Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Structure of the Core Vaccinia Virus Dna-Dependent Rna Polymerase Complex within 5.0Å range: probe atom residue distance (Å) B Occ J:Zn101 b:68.8 occ:1.00 SG J:CYS10 2.2 39.1 1.0 SG J:CYS7 2.2 37.0 1.0 SG J:CYS39 2.2 39.6 1.0 SG J:CYS40 2.3 40.3 1.0 CB J:CYS7 3.0 37.0 1.0 N J:CYS40 3.4 40.3 1.0 CB J:CYS10 3.4 39.1 1.0 N J:CYS10 3.4 39.1 1.0 CB J:CYS39 3.5 39.6 1.0 CB J:CYS40 3.6 40.3 1.0 CA J:CYS40 3.8 40.3 1.0 C J:CYS39 3.8 39.6 1.0 CA J:CYS10 4.0 39.1 1.0 CB J:THR9 4.0 35.0 1.0 CA J:CYS39 4.2 39.6 1.0 C J:THR9 4.4 35.0 1.0 CA J:CYS7 4.4 37.0 1.0 O J:CYS39 4.4 39.6 1.0 N J:THR9 4.5 35.0 1.0 CA J:THR9 4.5 35.0 1.0 CB J:ASN37 4.6 44.9 1.0 CG2 J:THR9 4.6 35.0 1.0 N J:GLY11 4.8 38.5 1.0 C J:CYS10 4.8 39.1 1.0 N J:CYS39 4.8 39.6 1.0 C J:CYS7 4.8 37.0 1.0 OG1 J:THR9 5.0 35.0 1.0

H.S.Hillen, J.Bartuli, C.Grimm, C.Dienemann, K.Bedenk, A.A.Szalay, U.Fischer, P.Cramer. Structural Basis of Poxvirus Transcription: Transcribing and Capping Vaccinia Complexes. Cell V. 179 1525 2019.
ISSN: ISSN 1097-4172
PubMed: 31835031
DOI: 10.1016/J.CELL.2019.11.023