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Zinc in PDB 6rhj: Crystal Structure of Human Carbonic Anhydrase Isozyme II with 4-(4- Benzyl-1,4-Diazepane-1-Carbonyl)BenzenesulfonamideEnzymatic activity of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 4-(4- Benzyl-1,4-Diazepane-1-Carbonyl)Benzenesulfonamide
All present enzymatic activity of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 4-(4- Benzyl-1,4-Diazepane-1-Carbonyl)Benzenesulfonamide:
4.2.1.1; Protein crystallography data
The structure of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 4-(4- Benzyl-1,4-Diazepane-1-Carbonyl)Benzenesulfonamide, PDB code: 6rhj
was solved by
M.Ferraroni,
A.Angeli,
C.T.Supuran,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Human Carbonic Anhydrase Isozyme II with 4-(4- Benzyl-1,4-Diazepane-1-Carbonyl)Benzenesulfonamide
(pdb code 6rhj). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human Carbonic Anhydrase Isozyme II with 4-(4- Benzyl-1,4-Diazepane-1-Carbonyl)Benzenesulfonamide, PDB code: 6rhj: Zinc binding site 1 out of 1 in 6rhjGo back to Zinc Binding Sites List in 6rhj
Zinc binding site 1 out
of 1 in the Crystal Structure of Human Carbonic Anhydrase Isozyme II with 4-(4- Benzyl-1,4-Diazepane-1-Carbonyl)Benzenesulfonamide
Mono view Stereo pair view
Reference:
N.Chiaramonte,
S.Bua,
A.Angeli,
M.Ferraroni,
I.Picchioni,
G.Bartolucci,
L.Braconi,
S.Dei,
E.Teodori,
C.T.Supuran,
M.N.Romanelli.
Sulfonamides Incorporating Piperazine Bioisosteres As Potent Human Carbonic Anhydrase I, II, IV and IX Inhibitors. Bioorg.Chem. V. 91 03130 2019.
Page generated: Wed Dec 16 12:40:17 2020
ISSN: ISSN 0045-2068 PubMed: 31374520 DOI: 10.1016/J.BIOORG.2019.103130 |
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