Zinc in PDB 6r7n: Structural Basis of Cullin-2 Ring E3 Ligase Regulation By the COP9 Signalosome

The binding sites of Zinc atom in the Structural Basis of Cullin-2 Ring E3 Ligase Regulation By the COP9 Signalosome (pdb code 6r7n). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Structural Basis of Cullin-2 Ring E3 Ligase Regulation By the COP9 Signalosome, PDB code: 6r7n:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Structural Basis of Cullin-2 Ring E3 Ligase Regulation By the COP9 Signalosome


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structural Basis of Cullin-2 Ring E3 Ligase Regulation By the COP9 Signalosome within 5.0Å range: probe atom residue distance (Å) B Occ R:Zn201 b:0.4 occ:1.00 O R:LEU52 2.1 0.0 1.0 OD1 R:ASP51 3.3 0.9 1.0 C R:LEU52 3.3 0.7 1.0 OD2 R:ASP51 3.3 0.9 1.0 CG R:ASP51 3.6 0.2 1.0 CA R:LEU52 4.0 0.3 1.0 CB R:LEU52 4.1 0.1 1.0 N R:LEU52 4.1 0.4 1.0 N R:CYS53 4.3 0.1 1.0 O R:CYS53 4.5 0.4 1.0 CA R:CYS53 4.6 0.1 1.0 C R:CYS53 4.7 0.2 1.0 C R:ASP51 5.0 0.7 1.0

Zinc binding site 2 out of 3 in the Structural Basis of Cullin-2 Ring E3 Ligase Regulation By the COP9 Signalosome


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structural Basis of Cullin-2 Ring E3 Ligase Regulation By the COP9 Signalosome within 5.0Å range: probe atom residue distance (Å) B Occ R:Zn202 b:0.9 occ:1.00 N R:CYS68 2.2 0.6 1.0 CA R:GLU67 2.5 0.1 1.0 CD1 R:ILE49 2.5 0.8 1.0 CG2 R:VAL70 2.5 0.2 1.0 C R:GLU67 2.7 0.9 1.0 CB R:VAL70 2.9 0.9 1.0 O R:GLU66 3.2 0.5 1.0 N R:GLU67 3.3 0.5 1.0 CA R:CYS68 3.3 0.8 1.0 CG1 R:ILE49 3.4 0.0 1.0 N R:THR69 3.5 0.8 1.0 C R:GLU66 3.5 0.4 1.0 N R:VAL70 3.6 0.6 1.0 CB R:GLU67 3.7 0.3 1.0 CB R:CYS68 3.7 0.5 1.0 C R:CYS68 3.8 0.3 1.0 CA R:VAL70 3.8 0.8 1.0 C R:THR69 3.9 0.9 1.0 O R:GLU67 3.9 0.8 1.0 CG R:GLU67 3.9 0.1 1.0 O R:ILE49 4.1 0.7 1.0 CG1 R:VAL70 4.1 0.5 1.0 OE1 B:GLN297 4.2 0.8 1.0 CA R:THR69 4.3 0.1 1.0 O R:THR69 4.4 0.6 1.0 CA R:ILE49 4.6 0.7 1.0 CB R:ILE49 4.6 0.7 1.0 C R:ILE49 4.8 0.3 1.0 O R:CYS68 4.9 0.5 1.0 CA R:GLU66 4.9 0.4 1.0

Zinc binding site 3 out of 3 in the Structural Basis of Cullin-2 Ring E3 Ligase Regulation By the COP9 Signalosome


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Structural Basis of Cullin-2 Ring E3 Ligase Regulation By the COP9 Signalosome within 5.0Å range: probe atom residue distance (Å) B Occ R:Zn203 b:0.4 occ:1.00 CB R:GLU55 2.6 0.7 1.0 CG R:GLU55 2.6 0.4 1.0 CB R:PHE81 2.6 0.5 1.0 CD2 R:PHE81 2.9 0.2 1.0 CA R:GLU55 3.1 0.9 1.0 CG R:PHE81 3.1 0.8 1.0 O R:GLU55 3.5 0.8 1.0 CA R:PHE81 3.6 0.6 1.0 N R:PHE81 3.6 0.5 1.0 N R:HIS82 3.7 0.3 1.0 ND1 R:HIS82 3.7 1.0 1.0 C R:GLU55 3.8 0.0 1.0 CD R:GLU55 4.1 0.8 1.0 C R:PHE81 4.1 0.8 1.0 CE2 R:PHE81 4.2 0.7 1.0 N R:GLU55 4.4 0.3 1.0 CD1 R:PHE81 4.5 0.8 1.0 CE1 R:HIS82 4.5 0.2 1.0 CG R:HIS82 4.7 0.6 1.0 C R:HIS80 4.7 1.0 1.0 OE2 R:GLU55 4.7 0.8 1.0 CB R:HIS82 4.8 1.0 1.0 CA R:HIS82 4.8 0.9 1.0 OE1 R:GLU55 4.9 0.2 1.0

S.V.Faull, A.M.C.Lau, C.Martens, Z.Ahdash, K.Hansen, H.Yebenes, C.Schmidt, F.Beuron, N.B.Cronin, E.P.Morris, A.Politis. Structural Basis of Cullin 2 Ring E3 Ligase Regulation By the COP9 Signalosome. Nat Commun V. 10 3814 2019.
ISSN: ESSN 2041-1723
PubMed: 31444342
DOI: 10.1038/S41467-019-11772-Y