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Zinc in PDB 6q8c: Neisseria Gonorrhoeae Leucyl-Trna Synthetase in Complex with 5'-O-(N- (L-Leucyl)-Sulfamoyl)UridineEnzymatic activity of Neisseria Gonorrhoeae Leucyl-Trna Synthetase in Complex with 5'-O-(N- (L-Leucyl)-Sulfamoyl)Uridine
All present enzymatic activity of Neisseria Gonorrhoeae Leucyl-Trna Synthetase in Complex with 5'-O-(N- (L-Leucyl)-Sulfamoyl)Uridine:
6.1.1.4; Protein crystallography data
The structure of Neisseria Gonorrhoeae Leucyl-Trna Synthetase in Complex with 5'-O-(N- (L-Leucyl)-Sulfamoyl)Uridine, PDB code: 6q8c
was solved by
L.Pang,
S.De Graef,
S.V.Strelkov,
S.D.Weeks,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6q8c:
The structure of Neisseria Gonorrhoeae Leucyl-Trna Synthetase in Complex with 5'-O-(N- (L-Leucyl)-Sulfamoyl)Uridine also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Neisseria Gonorrhoeae Leucyl-Trna Synthetase in Complex with 5'-O-(N- (L-Leucyl)-Sulfamoyl)Uridine
(pdb code 6q8c). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Neisseria Gonorrhoeae Leucyl-Trna Synthetase in Complex with 5'-O-(N- (L-Leucyl)-Sulfamoyl)Uridine, PDB code: 6q8c: Zinc binding site 1 out of 1 in 6q8cGo back to Zinc Binding Sites List in 6q8c
Zinc binding site 1 out
of 1 in the Neisseria Gonorrhoeae Leucyl-Trna Synthetase in Complex with 5'-O-(N- (L-Leucyl)-Sulfamoyl)Uridine
Mono view Stereo pair view
Reference:
M.Nautiyal,
S.De Graef,
L.Pang,
B.Gadakh,
S.V.Strelkov,
S.D.Weeks,
A.Van Aerschot.
Comparative Analysis of Pyrimidine Substituted Aminoacyl-Sulfamoyl Nucleosides As Potential Inhibitors Targeting Class I Aminoacyl-Trna Synthetases. Eur.J.Med.Chem. V. 173 154 2019.
Page generated: Wed Dec 16 12:33:47 2020
ISSN: ISSN 0223-5234 PubMed: 30995568 DOI: 10.1016/J.EJMECH.2019.04.003 |
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