Zinc in PDB 6o60: Crystal Structure of GGTASE3-FBXL2-SKP1 Complex

All present enzymatic activity of Crystal Structure of GGTASE3-FBXL2-SKP1 Complex:
2.5.1.60;

The structure of Crystal Structure of GGTASE3-FBXL2-SKP1 Complex, PDB code: 6o60 was solved by H.Wang, N.Zheng, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.45 / 2.50
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	86.843, 99.318, 151.202, 90.00, 90.00, 90.00
R / Rfree (%)	19.4 / 24.7

The binding sites of Zinc atom in the Crystal Structure of GGTASE3-FBXL2-SKP1 Complex (pdb code 6o60). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of GGTASE3-FBXL2-SKP1 Complex, PDB code: 6o60:

Zinc binding site 1 out of 1 in the Crystal Structure of GGTASE3-FBXL2-SKP1 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of GGTASE3-FBXL2-SKP1 Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn401 b:41.6 occ:1.00 OD1 B:ASP238 2.2 34.5 1.0 NE2 B:HIS290 2.2 35.7 1.0 SG B:CYS240 2.2 37.0 1.0 OD2 B:ASP238 2.5 39.1 1.0 CG B:ASP238 2.7 42.2 1.0 CD2 B:HIS290 3.0 34.4 1.0 CB B:CYS240 3.2 35.5 1.0 CE1 B:HIS290 3.3 36.1 1.0 N B:CYS240 3.9 32.1 1.0 CB B:ASP280 4.1 37.2 1.0 CA B:CYS240 4.1 33.6 1.0 CB B:ASP238 4.1 40.2 1.0 CG B:HIS290 4.3 35.8 1.0 ND1 B:HIS290 4.4 36.0 1.0 CE2 B:PHE289 4.4 41.9 1.0 CA B:ASP280 4.8 35.8 1.0 N B:TYR241 4.8 36.9 1.0 CD2 B:PHE289 4.8 39.6 1.0 N B:VAL239 4.9 49.6 1.0 CD2 B:TYR241 4.9 42.8 1.0 C B:CYS240 4.9 39.0 1.0 CA B:ASP238 5.0 44.2 1.0

S.Kuchay, H.Wang, A.Marzio, K.Jain, H.Homer, N.Fehrenbacher, M.R.Philips, N.Zheng, M.Pagano. GGTASE3 Is A Newly Identified Geranylgeranyltransferase Targeting A Ubiquitin Ligase. Nat.Struct.Mol.Biol. V. 26 628 2019.
ISSN: ESSN 1545-9985
PubMed: 31209342
DOI: 10.1038/S41594-019-0249-3