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Zinc in PDB 6lsh: Crystal Structure of the Enterovirus 71 Polymerase Elongation Complex (C2S6M Form)

Enzymatic activity of Crystal Structure of the Enterovirus 71 Polymerase Elongation Complex (C2S6M Form)

All present enzymatic activity of Crystal Structure of the Enterovirus 71 Polymerase Elongation Complex (C2S6M Form):
2.7.7.48;

Protein crystallography data

The structure of Crystal Structure of the Enterovirus 71 Polymerase Elongation Complex (C2S6M Form), PDB code: 6lsh was solved by R.Li, M.Wang, X.Jing, P.Gong, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 28.90 / 2.23
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 62.878, 77.380, 155.770, 90.00, 90.00, 90.00
R / Rfree (%) 20.8 / 24.5

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of the Enterovirus 71 Polymerase Elongation Complex (C2S6M Form) (pdb code 6lsh). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of the Enterovirus 71 Polymerase Elongation Complex (C2S6M Form), PDB code: 6lsh:

Zinc binding site 1 out of 1 in 6lsh

Go back to Zinc Binding Sites List in 6lsh
Zinc binding site 1 out of 1 in the Crystal Structure of the Enterovirus 71 Polymerase Elongation Complex (C2S6M Form)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Enterovirus 71 Polymerase Elongation Complex (C2S6M Form) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn502

b:45.7
occ:0.88
NE2 A:HIS271 2.0 52.6 1.0
NE2 A:HIS273 2.1 52.9 1.0
SG A:CYS282 2.1 42.5 1.0
CD2 A:HIS273 2.9 50.1 1.0
CE1 A:HIS271 3.0 53.6 1.0
CD2 A:HIS271 3.1 51.1 1.0
CE1 A:HIS273 3.2 56.5 1.0
CB A:CYS282 3.3 48.4 1.0
NE1 A:TRP5 3.8 49.8 1.0
CZ2 A:TRP5 4.1 52.0 1.0
ND1 A:HIS271 4.1 50.8 1.0
CG A:HIS273 4.1 56.1 1.0
CG A:HIS271 4.2 52.2 1.0
ND1 A:HIS273 4.2 60.4 1.0
CE2 A:TRP5 4.3 50.0 1.0
CA A:CYS282 4.4 46.9 1.0
CD1 A:TRP5 4.9 48.8 1.0

Reference:

M.Wang, R.Li, B.Shu, X.Jing, H.Q.Ye, P.Gong. Crystal Structure of the Enterovirus 71 Polymerase Elongation Complex (C2S6M Form) To Be Published.
Page generated: Wed Dec 16 12:16:51 2020

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