Zinc in PDB 6lsf: Crystal Structure of the Enterovirus 71 Polymerase Elongation Complex (C2S6RA/C2S6RB Form)

Enzymatic activity of Crystal Structure of the Enterovirus 71 Polymerase Elongation Complex (C2S6RA/C2S6RB Form)

All present enzymatic activity of Crystal Structure of the Enterovirus 71 Polymerase Elongation Complex (C2S6RA/C2S6RB Form):
2.7.7.48; 3.4.22.28; 3.4.22.29; 3.6.1.15;

Protein crystallography data

The structure of Crystal Structure of the Enterovirus 71 Polymerase Elongation Complex (C2S6RA/C2S6RB Form), PDB code: 6lsf was solved by M.Wang, B.Shu, X.Jing, P.Gong, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 28.73 / 2.15
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 61.350, 76.447, 155.004, 90.00, 90.00, 90.00
R / Rfree (%) 21.5 / 25.1

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of the Enterovirus 71 Polymerase Elongation Complex (C2S6RA/C2S6RB Form) (pdb code 6lsf). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of the Enterovirus 71 Polymerase Elongation Complex (C2S6RA/C2S6RB Form), PDB code: 6lsf:

Zinc binding site 1 out of 1 in 6lsf

Go back to Zinc Binding Sites List in 6lsf
Zinc binding site 1 out of 1 in the Crystal Structure of the Enterovirus 71 Polymerase Elongation Complex (C2S6RA/C2S6RB Form)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Enterovirus 71 Polymerase Elongation Complex (C2S6RA/C2S6RB Form) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn502

b:44.6
occ:0.76
 NE2 A:HIS273 1.9 50.0 1.0
NE2 A:HIS271 1.9 54.8 1.0
SG A:CYS282 2.1 40.2 1.0
CD2 A:HIS273 2.8 50.7 1.0
CE1 A:HIS271 2.9 54.2 1.0
CE1 A:HIS273 2.9 55.4 1.0
CD2 A:HIS271 3.0 51.0 1.0
CB A:CYS282 3.2 42.5 1.0
NE1 A:TRP5 3.9 42.5 1.0
CG A:HIS273 4.0 50.0 1.0
ND1 A:HIS273 4.0 57.7 1.0
ND1 A:HIS271 4.0 48.6 1.0
CG A:HIS271 4.1 46.4 1.0
CZ2 A:TRP5 4.2 49.1 1.0
CA A:CYS282 4.3 48.6 1.0
CE2 A:TRP5 4.4 46.9 1.0
CD1 A:TRP5 5.0 42.7 1.0

Reference:

M.Wang, R.Li, B.Shu, X.Jing, H.Q.Ye, P.Gong. Crystal Structure of the Enterovirus 71 Polymerase Elongation Complex (C2S6RA/C2S6RB Form) To Be Published.
Page generated: Wed Dec 16 12:16:46 2020

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