Zinc in PDB 6lnk: Candida Albicans Fructose-1,6-Bisphosphate Aldolase

All present enzymatic activity of Candida Albicans Fructose-1,6-Bisphosphate Aldolase:
4.1.2.13;

The structure of Candida Albicans Fructose-1,6-Bisphosphate Aldolase, PDB code: 6lnk was solved by Y.Huang, H.Cao, Y.Ren, J.Wan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.91 / 2.64
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	160.475, 56.758, 82.388, 90, 95.85, 90
R / Rfree (%)	19.8 / 25.9

The binding sites of Zinc atom in the Candida Albicans Fructose-1,6-Bisphosphate Aldolase (pdb code 6lnk). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Candida Albicans Fructose-1,6-Bisphosphate Aldolase, PDB code: 6lnk:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Candida Albicans Fructose-1,6-Bisphosphate Aldolase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Candida Albicans Fructose-1,6-Bisphosphate Aldolase within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:69.0 occ:1.00 NE2 A:HIS225 1.9 69.0 1.0 NE2 A:HIS109 2.0 55.6 1.0 ND1 A:HIS264 2.3 55.2 1.0 OE2 A:GLU173 2.3 59.1 1.0 OE1 A:GLU173 2.5 62.9 1.0 CD A:GLU173 2.7 60.5 1.0 CE1 A:HIS225 2.8 68.0 1.0 CD2 A:HIS225 3.0 63.1 1.0 CE1 A:HIS109 3.0 59.3 1.0 CD2 A:HIS109 3.1 51.5 1.0 CE1 A:HIS264 3.1 57.7 1.0 CG A:HIS264 3.4 53.2 1.0 CB A:HIS264 3.8 53.0 1.0 O A:HOH526 3.9 58.8 1.0 ND1 A:HIS225 3.9 68.8 1.0 CG A:HIS225 4.1 66.6 1.0 ND1 A:HIS109 4.1 64.3 1.0 CG A:HIS109 4.2 57.7 1.0 CG A:GLU173 4.2 64.6 1.0 NE2 A:HIS264 4.3 51.5 1.0 CD2 A:HIS264 4.4 54.1 1.0 OD2 A:ASP143 5.0 65.3 1.0 CB A:GLU173 5.0 60.7 1.0

Zinc binding site 2 out of 2 in the Candida Albicans Fructose-1,6-Bisphosphate Aldolase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Candida Albicans Fructose-1,6-Bisphosphate Aldolase within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn401 b:63.4 occ:1.00 NE2 B:HIS225 1.8 63.6 1.0 NE2 B:HIS109 1.9 63.7 1.0 OE2 B:GLU173 2.2 59.1 1.0 OE1 B:GLU173 2.2 62.9 1.0 O B:HOH501 2.2 53.9 1.0 ND1 B:HIS264 2.3 57.5 1.0 CD B:GLU173 2.5 60.5 1.0 CE1 B:HIS225 2.7 61.9 1.0 CE1 B:HIS109 2.8 59.4 1.0 CD2 B:HIS225 2.8 62.1 1.0 CE1 B:HIS264 3.0 62.0 1.0 CD2 B:HIS109 3.1 63.8 1.0 CG B:HIS264 3.4 59.9 1.0 ND1 B:HIS225 3.8 63.9 1.0 CB B:HIS264 3.9 58.8 1.0 CG B:HIS225 3.9 66.2 1.0 ND1 B:HIS109 3.9 67.1 1.0 CG B:GLU173 4.0 64.6 1.0 CG B:HIS109 4.1 62.3 1.0 NE2 B:HIS264 4.2 63.5 1.0 CD2 B:HIS264 4.4 60.3 1.0 OD1 B:ASP143 4.8 68.9 1.0 CB B:GLU173 4.8 60.7 1.0 CG B:ASP143 4.9 71.0 1.0

Y.Huang, H.Cao, Y.Ren, J.Wan. Candida Albicans Fructose-1,6-Bisphosphate Aldolase To Be Published.