Zinc in PDB 6ins: X-Ray Analysis of the Single Chain B29-A1 Peptide-Linked Insulin Molecule. A Completely Inactive Analogue

The structure of X-Ray Analysis of the Single Chain B29-A1 Peptide-Linked Insulin Molecule. A Completely Inactive Analogue, PDB code: 6ins was solved by U.Derewenda, Z.Derewenda, E.J.Dodson, G.G.Dodson, X.Bing, J.Markussen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	N/A / 2.00
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	79.220, 79.220, 37.750, 90.00, 90.00, 120.00
R / Rfree (%)	n/a / n/a

The binding sites of Zinc atom in the X-Ray Analysis of the Single Chain B29-A1 Peptide-Linked Insulin Molecule. A Completely Inactive Analogue (pdb code 6ins). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the X-Ray Analysis of the Single Chain B29-A1 Peptide-Linked Insulin Molecule. A Completely Inactive Analogue, PDB code: 6ins:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the X-Ray Analysis of the Single Chain B29-A1 Peptide-Linked Insulin Molecule. A Completely Inactive Analogue


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of X-Ray Analysis of the Single Chain B29-A1 Peptide-Linked Insulin Molecule. A Completely Inactive Analogue within 5.0Å range: probe atom residue distance (Å) B Occ E:Zn30 b:19.5 occ:0.33 NE2 E:HIS10B 1.9 19.4 1.0 O E:HOH31 2.3 14.1 0.3 CE1 E:HIS10B 2.7 24.1 1.0 CD2 E:HIS10B 3.0 4.6 1.0 O E:HOH103 3.7 39.9 0.3 ND1 E:HIS10B 3.9 13.6 1.0 CG E:HIS10B 4.1 10.0 1.0 O E:LEU6B 4.6 12.9 1.0

Zinc binding site 2 out of 2 in the X-Ray Analysis of the Single Chain B29-A1 Peptide-Linked Insulin Molecule. A Completely Inactive Analogue


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of X-Ray Analysis of the Single Chain B29-A1 Peptide-Linked Insulin Molecule. A Completely Inactive Analogue within 5.0Å range: probe atom residue distance (Å) B Occ F:Zn30 b:21.5 occ:0.33 O F:HOH81 1.2 6.5 0.3 NE2 F:HIS10D 2.1 6.4 1.0 CE1 F:HIS10D 3.0 15.5 1.0 CD2 F:HIS10D 3.1 10.8 1.0 O F:HOH48 3.6 47.3 1.0 ND1 F:HIS10D 4.1 10.6 1.0 CG F:HIS10D 4.2 26.2 1.0 O F:HOH89 4.4 57.6 1.0

U.Derewenda, Z.Derewenda, E.J.Dodson, G.G.Dodson, X.Bing, J.Markussen. X-Ray Analysis of the Single Chain B29-A1 Peptide-Linked Insulin Molecule. A Completely Inactive Analogue. J.Mol.Biol. V. 220 425 1991.
ISSN: ISSN 0022-2836
PubMed: 1856866
DOI: 10.1016/0022-2836(91)90022-X