Zinc in PDB 6dnh: Cryo-Em Structure of Human Cpsf-160-WDR33-Cpsf-30-Pas Rna Complex at 3.4 A Resolution

The binding sites of Zinc atom in the Cryo-Em Structure of Human Cpsf-160-WDR33-Cpsf-30-Pas Rna Complex at 3.4 A Resolution (pdb code 6dnh). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Cryo-Em Structure of Human Cpsf-160-WDR33-Cpsf-30-Pas Rna Complex at 3.4 A Resolution, PDB code: 6dnh:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Cryo-Em Structure of Human Cpsf-160-WDR33-Cpsf-30-Pas Rna Complex at 3.4 A Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of Human Cpsf-160-WDR33-Cpsf-30-Pas Rna Complex at 3.4 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn301 b:30.0 occ:1.00 NE2 C:HIS59 2.2 39.9 1.0 SG C:CYS49 2.5 40.0 1.0 SG C:CYS41 2.8 40.0 1.0 SG C:CYS55 2.9 40.0 1.0 CE1 C:HIS59 3.0 39.9 1.0 CD2 C:HIS59 3.1 39.9 1.0 CB C:CYS49 3.2 40.0 1.0 CB C:CYS55 3.7 40.0 1.0 CB C:CYS41 3.8 40.0 1.0 ND1 C:HIS59 4.0 39.9 1.0 CG C:HIS59 4.1 39.9 1.0 CB C:PHE44 4.5 40.6 1.0 O C:PHE57 4.7 30.0 1.0 CA C:CYS49 4.7 30.0 1.0 CB C:PHE57 4.8 40.6 1.0 N C:PHE44 5.0 30.0 1.0 O C:ARG58 5.0 30.0 1.0

Zinc binding site 2 out of 3 in the Cryo-Em Structure of Human Cpsf-160-WDR33-Cpsf-30-Pas Rna Complex at 3.4 A Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of Human Cpsf-160-WDR33-Cpsf-30-Pas Rna Complex at 3.4 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn302 b:30.0 occ:1.00 NE2 C:HIS86 2.0 46.1 1.0 SG C:CYS76 2.5 69.5 1.0 CE1 C:HIS86 2.6 46.1 1.0 SG C:CYS68 3.0 30.0 1.0 SG C:CYS82 3.1 53.0 1.0 CD2 C:HIS86 3.2 46.1 1.0 CB C:CYS82 3.5 53.0 1.0 ND1 C:HIS86 3.8 46.1 1.0 CB C:CYS76 3.9 69.5 1.0 CB C:CYS68 4.0 30.0 1.0 CG C:HIS86 4.1 46.1 1.0 N6 E:A2 4.5 20.0 1.0 O C:PHE84 4.6 33.8 1.0 O C:GLY79 4.6 42.0 1.0 CB C:PHE84 4.7 54.0 1.0 CB C:TRP71 4.9 55.1 1.0

Zinc binding site 3 out of 3 in the Cryo-Em Structure of Human Cpsf-160-WDR33-Cpsf-30-Pas Rna Complex at 3.4 A Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Cryo-Em Structure of Human Cpsf-160-WDR33-Cpsf-30-Pas Rna Complex at 3.4 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn303 b:30.0 occ:1.00 NE2 C:HIS114 2.3 44.4 1.0 SG C:CYS110 2.4 37.4 1.0 SG C:CYS96 2.7 39.9 1.0 CB C:CYS105 3.0 37.3 1.0 CB C:CYS110 3.1 37.4 1.0 CE1 C:HIS114 3.2 44.4 1.0 CD2 C:HIS114 3.2 44.4 1.0 CB C:CYS96 3.5 39.9 1.0 SG C:CYS105 3.5 37.3 1.0 ND1 C:HIS114 4.2 44.4 1.0 CG C:HIS114 4.3 44.4 1.0 CA C:CYS105 4.4 27.6 1.0 CA C:CYS110 4.6 28.6 1.0 CZ C:TYR99 4.6 39.7 1.0 N6 E:A5 4.6 20.0 1.0 CE1 C:TYR99 4.7 39.7 1.0 OD1 C:ASN107 4.9 38.9 1.0 O C:PHE112 4.9 33.0 1.0 CA C:CYS96 4.9 29.3 1.0 OH C:TYR99 4.9 39.7 1.0 CE2 C:TYR99 4.9 39.7 1.0 CD1 C:TYR99 5.0 39.7 1.0 O C:ASN107 5.0 27.7 1.0

Y.Sun, Y.Zhang, K.Hamilton, J.L.Manley, Y.Shi, T.Walz, L.Tong. Molecular Basis For the Recognition of the Human Aauaaa Polyadenylation Signal. Proc. Natl. Acad. Sci. V. 115 E1419 2018U.S.A..
ISSN: ESSN 1091-6490
PubMed: 29208711
DOI: 10.1073/PNAS.1718723115