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Atomistry » Zinc » PDB 6cef-6clk » 6ck6 » |
Zinc in PDB 6ck6: Crystal Structure of MNK2-D228G in Complex with InhibitorEnzymatic activity of Crystal Structure of MNK2-D228G in Complex with Inhibitor
All present enzymatic activity of Crystal Structure of MNK2-D228G in Complex with Inhibitor:
2.7.11.1; Protein crystallography data
The structure of Crystal Structure of MNK2-D228G in Complex with Inhibitor, PDB code: 6ck6
was solved by
Q.Han,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of MNK2-D228G in Complex with Inhibitor
(pdb code 6ck6). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of MNK2-D228G in Complex with Inhibitor, PDB code: 6ck6: Zinc binding site 1 out of 1 in 6ck6Go back to Zinc Binding Sites List in 6ck6
Zinc binding site 1 out
of 1 in the Crystal Structure of MNK2-D228G in Complex with Inhibitor
Mono view Stereo pair view
Reference:
S.H.Reich,
P.A.Sprengeler,
G.G.Chiang,
J.R.Appleman,
J.Chen,
J.Clarine,
B.Eam,
J.T.Ernst,
Q.Han,
V.K.Goel,
E.Z.R.Han,
V.Huang,
I.N.J.Hung,
A.Jemison,
K.A.Jessen,
J.Molter,
D.Murphy,
M.Neal,
G.S.Parker,
M.Shaghafi,
S.Sperry,
J.Staunton,
C.R.Stumpf,
P.A.Thompson,
C.Tran,
S.E.Webber,
C.J.Wegerski,
H.Zheng,
K.R.Webster.
Structure-Based Design of Pyridone-Aminal EFT508 Targeting Dysregulated Translation By Selective Mitogen-Activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition. J. Med. Chem. V. 61 3516 2018.
Page generated: Mon Oct 28 18:55:34 2024
ISSN: ISSN 1520-4804 PubMed: 29526098 DOI: 10.1021/ACS.JMEDCHEM.7B01795 |
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