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Zinc in PDB 6bd4: Crystal Structure of Human Apo-FRIZZLED4 Receptor

Protein crystallography data

The structure of Crystal Structure of Human Apo-FRIZZLED4 Receptor, PDB code: 6bd4 was solved by S.Yang, Y.Wu, M.Pu, Y.Chen, S.Dong, Y.Guo, G.Y.Han, R.C.Stevens, S.Zhao, F.Xu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 30.00 / 2.40
Space group C 2 2 21
Cell size a, b, c (Å), α, β, γ (°) 61.670, 154.690, 114.400, 90.00, 90.00, 90.00
R / Rfree (%) 21 / 23.3

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of Human Apo-FRIZZLED4 Receptor (pdb code 6bd4). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human Apo-FRIZZLED4 Receptor, PDB code: 6bd4:

Zinc binding site 1 out of 1 in 6bd4

Go back to Zinc Binding Sites List in 6bd4
Zinc binding site 1 out of 1 in the Crystal Structure of Human Apo-FRIZZLED4 Receptor


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human Apo-FRIZZLED4 Receptor within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1101

b:81.7
occ:1.00
SG A:CYS1009 2.3 89.6 1.0
SG A:CYS1042 2.4 99.4 1.0
SG A:CYS1039 2.5 93.0 1.0
SG A:CYS1006 2.6 90.3 1.0
CB A:CYS1006 3.2 86.2 1.0
CB A:CYS1039 3.3 88.0 1.0
CB A:CYS1009 3.4 87.9 1.0
CB A:CYS1042 3.6 97.5 1.0
N A:CYS1009 3.8 87.3 1.0
N A:CYS1042 4.0 95.5 1.0
CA A:CYS1009 4.1 88.7 1.0
CG2 A:VAL1044 4.3 91.5 1.0
CA A:CYS1042 4.4 97.5 1.0
CB A:TYR1011 4.4 89.2 1.0
N A:GLY1010 4.6 88.4 1.0
CB A:VAL1008 4.7 85.8 1.0
N A:TYR1011 4.7 88.3 1.0
CA A:CYS1006 4.7 86.6 1.0
C A:CYS1009 4.7 94.7 1.0
CB A:LEU1041 4.8 95.9 1.0
N A:GLY1043 4.8 96.6 1.0
CA A:CYS1039 4.8 88.4 1.0
C A:VAL1008 4.9 90.7 1.0

Reference:

S.Yang, Y.Wu, T.H.Xu, P.W.De Waal, Y.He, M.Pu, Y.Chen, Z.J.Debruine, B.Zhang, S.A.Zaidi, P.Popov, Y.Guo, G.W.Han, Y.Lu, K.Suino-Powell, S.Dong, K.G.Harikumar, L.J.Miller, V.Katritch, H.E.Xu, W.Shui, R.C.Stevens, K.Melcher, S.Zhao, F.Xu. Crystal Structure of the Frizzled 4 Receptor in A Ligand-Free State. Nature V. 560 666 2018.
ISSN: ESSN 1476-4687
PubMed: 30135577
DOI: 10.1038/S41586-018-0447-X
Page generated: Mon Oct 28 17:55:56 2024

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