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Atomistry » Zinc » PDB 5mq1-5n1r » 5n0e » |
Zinc in PDB 5n0e: Crystal Structure of Human Carbonic Anhydrase II in Complex with (S)- 4-(6,7-Dihydroxy-1-Phenyl-3,4-Tetrahydroisoquinoline-1H-2-Carbonyl) Benzenesulfonamide.Enzymatic activity of Crystal Structure of Human Carbonic Anhydrase II in Complex with (S)- 4-(6,7-Dihydroxy-1-Phenyl-3,4-Tetrahydroisoquinoline-1H-2-Carbonyl) Benzenesulfonamide.
All present enzymatic activity of Crystal Structure of Human Carbonic Anhydrase II in Complex with (S)- 4-(6,7-Dihydroxy-1-Phenyl-3,4-Tetrahydroisoquinoline-1H-2-Carbonyl) Benzenesulfonamide.:
4.2.1.1; Protein crystallography data
The structure of Crystal Structure of Human Carbonic Anhydrase II in Complex with (S)- 4-(6,7-Dihydroxy-1-Phenyl-3,4-Tetrahydroisoquinoline-1H-2-Carbonyl) Benzenesulfonamide., PDB code: 5n0e
was solved by
A.Di Fiore,
G.De Simone,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Human Carbonic Anhydrase II in Complex with (S)- 4-(6,7-Dihydroxy-1-Phenyl-3,4-Tetrahydroisoquinoline-1H-2-Carbonyl) Benzenesulfonamide.
(pdb code 5n0e). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human Carbonic Anhydrase II in Complex with (S)- 4-(6,7-Dihydroxy-1-Phenyl-3,4-Tetrahydroisoquinoline-1H-2-Carbonyl) Benzenesulfonamide., PDB code: 5n0e: Zinc binding site 1 out of 1 in 5n0eGo back to Zinc Binding Sites List in 5n0e
Zinc binding site 1 out
of 1 in the Crystal Structure of Human Carbonic Anhydrase II in Complex with (S)- 4-(6,7-Dihydroxy-1-Phenyl-3,4-Tetrahydroisoquinoline-1H-2-Carbonyl) Benzenesulfonamide.
Mono view Stereo pair view
Reference:
E.Bruno,
M.R.Buemi,
A.Di Fiore,
L.De Luca,
S.Ferro,
A.Angeli,
R.Cirilli,
D.Sadutto,
V.Alterio,
S.M.Monti,
C.T.Supuran,
G.De Simone,
R.Gitto.
Probing Molecular Interactions Between Human Carbonic Anhydrases (Hcas) and A Novel Class of Benzenesulfonamides. J. Med. Chem. V. 60 4316 2017.
Page generated: Wed Dec 16 06:33:59 2020
ISSN: ISSN 1520-4804 PubMed: 28453941 DOI: 10.1021/ACS.JMEDCHEM.7B00264 |
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