Zinc in PDB 5n0b: Crystal Structure of the Tetanus Neurotoxin in Complex with GD1A

All present enzymatic activity of Crystal Structure of the Tetanus Neurotoxin in Complex with GD1A:
3.4.24.68;

The structure of Crystal Structure of the Tetanus Neurotoxin in Complex with GD1A, PDB code: 5n0b was solved by G.Masuyer, J.Conrad, P.Stenmark, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	68.50 / 2.60
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	152.695, 136.840, 92.630, 90.00, 90.07, 90.00
R / Rfree (%)	20.3 / 24.7

The binding sites of Zinc atom in the Crystal Structure of the Tetanus Neurotoxin in Complex with GD1A (pdb code 5n0b). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of the Tetanus Neurotoxin in Complex with GD1A, PDB code: 5n0b:

Zinc binding site 1 out of 1 in the Crystal Structure of the Tetanus Neurotoxin in Complex with GD1A


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Tetanus Neurotoxin in Complex with GD1A within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1401 b:70.9 occ:1.00 NE2 A:HIS233 2.5 47.6 1.0 NE2 A:HIS237 2.5 47.1 1.0 O A:HOH1584 2.9 39.3 1.0 CD2 A:HIS233 3.0 46.2 1.0 CD2 A:HIS237 3.3 45.1 1.0 CE1 A:HIS237 3.6 45.6 1.0 CE1 A:HIS233 3.7 48.2 1.0 CG A:GLU271 3.9 65.2 1.0 O A:HOH1596 4.0 53.8 1.0 OE2 A:GLU234 4.1 48.2 1.0 CG A:HIS233 4.3 44.4 1.0 CG A:HIS237 4.5 43.4 1.0 ND1 A:HIS233 4.6 47.8 1.0 CB A:GLU271 4.6 57.6 1.0 ND1 A:HIS237 4.6 44.5 1.0 OE2 A:GLU271 4.8 81.9 1.0 OE1 A:GLU234 4.8 49.6 1.0 CD A:GLU234 4.8 47.0 1.0 CD A:GLU271 4.8 73.5 1.0 CA A:GLU271 4.8 52.0 1.0 CG2 A:THR274 5.0 45.4 1.0

G.Masuyer, J.Conrad, P.Stenmark. The Structure of the Tetanus Toxin Reveals pH-Mediated Domain Dynamics. Embo Rep. V. 18 1306 2017.
ISSN: ESSN 1469-3178
PubMed: 28645943
DOI: 10.15252/EMBR.201744198